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TranscriptomicsMLLT10 gene recombinations in pediatric T-Acute Lymphoblastic Leukemia
MLLT10, a 24 exons gene at 10p12, is known in leukemogenesis as partner of MLL or PICALM and recently NAP1L1. We identified HNRNPH1 and DDX3X, genes involved in RNA processing, as new MLLT10 partners in 2 cases of pediatric NOTCH1 positive T-ALL. HNRNPH1/5q35 encodes for a member of the ubiquitously...
ORGANISM(S): Homo sapiens 
2013-07-03 | E-GEOD-42765 | biostudies-arrayexpress
TranscriptomicsLinking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia
GEP class prediction in association with CI-FISH (42 candidate genes) and patient MRD stratification Combined Interphase FISH (CI-FISH) for 42 candidate genes and Single Nucleotide Polymorphism (SNP) arrays were applied in a series of 51 T-ALL patients enrolled in Italy into the AIEOP-BFM ALL2000 pr...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-GEOD-39816 | biostudies-arrayexpress
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