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Although the clinical differences between hemodialysis (HD) and peritoneal dialysis (PD) are well described, the specific biological mechanisms that cause these differences remain a subject of ongoing research. Omics-based approaches may help to elucidate these differences. To address this aim, we p...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD076533 | Pride
Here we analysed the role of yeast Senataxin (Sen1) in coordinating replication with transcription and in protecting genome integrity. Senataxin is mutated in the two severe neurodegenerative diseases AOA2 and ALS4. We show that a fraction of Sen1/Senataxin DNA/RNA helicase associates with replicati...
ORGANISM(S): Saccharomyces cerevisiae 
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