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TranscriptomicsM-OM-^CB-dependent yabJ-spoVG operon involved in regulation of extracellular nuclease, lipase and protease expression in Staphylococcus aureus
The alternative sigma factor M-OM-^CB of Staphylococcus aureus is involved in the coordination of the general stress response, expression of virulence determinants and modulation of antibiotic resistance levels. It controls a large regulon, either directly by recognizing conserved M-OM-^CB promoter ...
ORGANISM(S): Staphylococcus aureus 
2011-11-23 | E-GEOD-30115 | biostudies-arrayexpress
TranscriptomicsGdpS contributes to Staphylococcus aureus biofilm formation by regulation of eDNA release
In Staphylococcus aureus, the role of the GGDEF domain containing protein GdpS remains poorly understood. Previous studies reported that gdpS mutant strains had decreased biofilm formation due to changes in icaADBC expression that were independent of cyclic-di-GMP levels. We deleted gdpS in three un...
ORGANISM(S): Staphylococcus aureus 
2014-06-30 | E-GEOD-48656 | biostudies-arrayexpress
TranscriptomicsDaptomycin-Resistance Mechanisms in Clinically-Derived Staphylococcus aureus Strains Assessed by a Combined Transcriptomics and Proteomics Approach
Objectives: Development of daptomycin resistance (DAPR) in Staphylococcus aureus is associated with clinical treatment failures. Mechanism(s) of such resistance has not been clearly defined. Methods: We studied an isogenic daptomycin-susceptible (DAPS) and daptomycin-resistant (DAPR) S. aureus stra...
ORGANISM(S): Staphylococcus aureus 
2011-12-02 | E-GEOD-28632 | biostudies-arrayexpress
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