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ProteomicsDEAD box RNA helicase 5 and 17 are novel host factors for Sindbis virus infection.
The DEAD-box ATP-dependent RNA helicases DDX5 and DDX17 play a role in many aspects of cellular RNA biology, including metabolism, translation, splicing, transcription regulation, ribosome biogenesis, mRNA nuclear export, and miRNA processing. Moreover, both RNA helicases were found to either promot...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD044867 | Pride
Sindbis virus Ddx5 Helicase Ddx17 Rna 
TranscriptomicsIdentification of RNase L-dependent, 3M-bM-^@M-2-end-modified, viral small RNAs in Sindbis virus-infected mammalian cells
Small RNAs play a critical role in host-pathogen interaction. In insects, for instance, small RNA-mediated silencing or RNA interference (RNAi) represents the main antiviral defense system. However, the antiviral role of RNAi has not been clearly proven in higher vertebrates. On the contrary, it is ...
ORGANISM(S): Chlorocebus aethiops 
2013-11-19 | E-GEOD-48831 | biostudies-arrayexpress
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