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UnknownMulti-omic lineage tracing predicts the transcriptional, epigenetic and genetic determinants of cancer evolution.
Not available
S-EPMC11366763 | biostudies-literature
ProteomicsFibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis
Fibro adipogenic progenitors (FAPs) promote satellite cell differentiation in adult skeletal muscle regeneration. However, in pathological conditions, FAPs are responsible for fibrosis and fatty infiltrations. Here we show that the NOTCH pathway negatively modulates FAP differentiation both in vitro...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-24 | PXD014195 | Pride
Adipogenesis Notch Inflammation Muscular dystrophy Myopathies Skeletal muscle regeneration Mass cytometry Fibro adipogenic progenitors Proteome 
ProteomicsStructural obstruction to full DNA replication in the chromatin of terminally differentiated skeletal muscle cells
Terminal cell differentiation is often associated with permanent withdrawal from proliferation, termed the postmitotic state. Though widespread among vertebrates and determinant for their biology, the molecular underpinnings of this state are poorly understood. Postmitotic skeletal muscle myotubes c...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-01-13 | MSV000096839 | MassIVE
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