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MetabolomicsDeletion of Gja1 in myocardium emerges ventricular arrhythmia and tachycardia by reprogramming proline metabolism
Connexin43 (Cx43) is the predominant connexin in working myocardium. Its expression decreases in various cardiovascular diseases, and accompanied by ventricular arrhythmias (VAs). However, molecular mechanisms underlying increased arrhythmogenesis remained unclear. Here we established iPSC-derived c...
2025-11-11 | MTBLS13302 | MetaboLights
TranscriptomicsConnexin-dependent transcellular transcriptomic networks in mouse brain
Microarray experiments have generally focused on magnitude of gene expression changes in pathological conditions, thereby using the method as a high throughput screen to identify candidate marker genes and/or to validate phenotypic differences. We have used novel strategies to extract additional in...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-6355 | biostudies-arrayexpress
UnknownGJA1 Expression and Its Prognostic Value in Cervical Cancer.
Not available
S-EPMC7709497 | biostudies-literature
UnknownCx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport.
Not available
S-EPMC5682029 | biostudies-literature
UnknownTwo novel GJA1 variants in oculodentodigital dysplasia.
Not available
S-EPMC6732303 | biostudies-literature
UnknownGJA1 (connexin43) is a key regulator of Alzheimer's disease pathogenesis.
Not available
S-EPMC6303945 | biostudies-literature
UnknownProtective mitochondrial fission induced by stress-responsive protein GJA1-20k.
Not available
S-EPMC8492060 | biostudies-literature
GenomicsTranscriptomics profiling of white adipose tissue of macrophage-specific Gja1 Knockout mice fed a normal chow diet (NCD) and high fat diet (HFD)
Transcriptomics profiling of white adipose tissue of macrophage-specific Gja1 Knockout mice fed a normal chow diet (NCD) and high fat diet (HFD)
PRJNA842353 | ENA
TranscriptomicsTranscriptomics profiling of white adipose tissue of macrophage-specific Gja1 Knockout mice fed a normal chow diet (NCD) and high fat diet (HFD)
Adipose mRNA profiles of wild-type and Gja1 knockout (tamoxifen-induced Csf1r-CreER/ Gja1(floxed/floxed)) mice were generated by deep sequencing.
ORGANISM(S): Mus musculus 
2022-06-01 | GSE204794 | GEO
UnknownGJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base.
Not available
S-EPMC9448326 | biostudies-literature
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