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TranscriptomicsRNA pol II ChIP on chip (RPCC)
Adaptation of the ChIP-on-chip protocol, to calculate genomic transcription rates in S. cerevisiae. Keywords: ChIP-chip There are 3 different experimental conditions: -Yeast cell growing exponentially in YPD. -Yeast cell stopped after 2 h of changing them to YPGal. -Yeast cell growing exponentiall...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-14060 | biostudies-arrayexpress
TranscriptomicsEnvironment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
Macrophages reside in essentially all tissues of the body and play key roles in innate and adaptive immune responses. Distinct populations of tissue macrophages also acquire context-specific functions that are important for normal tissue homeostasis. To investigate mechanisms responsible for tissue-...
ORGANISM(S): Mus musculus 
2014-12-04 | E-GEOD-62826 | biostudies-arrayexpress
MetabolomicsAn Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors
Direct infusion high-resolution mass spectrometry (DIHRMS) is a novel, high-throughput approach to rapidly and accurately profile hundreds of lipids in human serum without prior chromatography, facilitating in-depth lipid phenotyping for large epidemiological studies to reveal the detailed associati...
2024-02-02 | MTBLS4461 | MetaboLights
TranscriptomicsTranscriptomic assessment of resistance to effects of an aryl hydrocarbon receptor (AHR) agonist in embryos of Atlantic killifish (Fundulus heteroclitus) from a marine Superfund site
This study presents statistical analyses of gene expression in 5, 10 and 15 day post-fertilization (dpf) embryos of the teleost Fundulus heteroclitus treated with control vehicle (DMSO) or a potent non-ortho-PCB (PCB-126; 3,3’,4,4’,5-pentachlorobiphenyl). The embryos were from two populations: a cl...
ORGANISM(S): Fundulus heteroclitus 
2011-06-06 | E-GEOD-25245 | biostudies-arrayexpress
TranscriptomicsTranslation profiling of fission yeast wild type and rng3-65 fission yeast to identify changes in th enumber of ribosomes associated with specific transcripts
Genome-wide translational profiling of rng3-65 compared to wild type cells. We used sucrose gradients to separate RNAs according to the number of associated ribosomes (a surrogate for translational efficiency). Preparation of the extracts and fractionation was carried out as described in Lackner e...
ORGANISM(S): Schizosaccharomyces pombe 
2008-12-23 | E-TABM-565 | biostudies-arrayexpress
TranscriptomicsDNA microarray comparison of gene expression patterns in Paracoccidioides brasiliensis mycelia and yeasts in vitro.
Paracoccidioides brasiliensis is a thermally dimorphic fungus, which causes the most prevalent systemic mycosis in Latin America. Infection is initiated by inhalation of conidia or mycelial fragments by the host, followed by further differentiation into the yeast form. Information regarding gene e...
ORGANISM(S): Paracoccidioides brasiliensis 
2009-05-07 | E-GEOD-15511 | biostudies-arrayexpress
TranscriptomicsIn-Vivo Fusion of Human Cancer and Hamster Stromal Cells Permanently Transduces and Transcribes Human DNA
The heterotransplantation of human tumors to immune-deprived rodents has become an important preclinical tool for evaluating human tumor biology and responsiveness to therapeutic agents, based on the supposition that they reflect their original human origin. However, we demonstrate that such tumors ...
ORGANISM(S): Homo sapiens 
2016-07-29 | E-GEOD-58277 | biostudies-arrayexpress
TranscriptomicsFunctional Study of the Chicken microRNAs miR-143 and miR-10a
MicroRNA (miRNA) is a family of small regulatory RNA that post-transcriptionally regulates many biological functions including growth and development. Chicken miR-143 and miR-10a are expressed in both the embryonic and post-hatch chick in a spatio-temporal manner. In order to study the functions of ...
ORGANISM(S): Gallus gallus 
2010-05-16 | E-GEOD-16653 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in resting human skeletal muscle of sedentary and highly-trained individuals.
We used gene microarray analysis to compare the global expression profile of genes involved in adaptation to exercise training in skeletal muscle from chronically strength/resistance trained (ST), endurance trained (ET) and untrained control subjects (Con). Resting skeletal muscle samples (~100mg) ...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-9405 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse macrophage responses to all-trans retinoic acid between wild type and NCoR-/- mice
Comparison of mouse macrophage responses to all-trans retinoic acid between wild-type and NCoR-/- mice.
ORGANISM(S): Mus musculus 
2006-11-06 | E-MEXP-37 | biostudies-arrayexpress
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