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MetabolomicsThe metabolic response of marine copepods to environmental warming and ocean acidification in the absence of food
Marine copepods are central to the productivity and biogeochemistry of marine ecosystems. Nevertheless, the direct and indirect effects of climate change on their metabolic functioning remain poorly understood. Here, we use metabolomics, the unbiased study of multiple low molecular weight organic me...
2015-10-13 | MTBLS91 | MetaboLights
ProteomicsProteomic profiles of bona fide RNA-binding proteins across E. coli growth curve in M9LB media.
Dynamic interactions between RNA and RNA-binding proteins (RBPs) regulate a broad spectrum of bacterial functions. Here, we have characterised how the RBPome is dynamically rewired during the E. coli life cycle. We applied Orthogonal Organic Phase Separation (OOPS) coupled with an RNase digestion st...
ORGANISM(S): Escherichia coli 
2024-03-20 | PXD043373 | Pride
Tmt Rna-binding proteins Oops Bacterial growth curve 
TranscriptomicsBrugia malayi mature vs immature microfilariae
Filarial nematodes are arthropod-borne nematodes that cause a variety of economically important diseases such as onchocerciasis (river blindness), lymphatic filariasis, and heartworm disease. The most widespread filarial disease of humans is lymphatic filariasis, caused by worms in the genera Wuche...
ORGANISM(S): Brugia malayi 
2010-05-22 | E-GEOD-14940 | biostudies-arrayexpress
TranscriptomicsMature vs immature microfilariae
Filarial nematodes are arthropod-borne nematodes that cause a variety of economically important diseases such as onchocerciasis (river blindness), lymphatic filariasis, and heartworm disease. The most widespread filarial disease of humans is lymphatic filariasis, caused by worms in the genera Wuche...
ORGANISM(S): Brugia pahangi 
2009-10-01 | E-GEOD-15017 | biostudies-arrayexpress
TranscriptomicsBrugia pahangi mature vs immature microfilariae
Filarial nematodes are arthropod-borne nematodes that cause a variety of economically important diseases such as onchocerciasis (river blindness), lymphatic filariasis, and heartworm disease. The most widespread filarial disease of humans is lymphatic filariasis, caused by worms in the genera Wuche...
ORGANISM(S): Brugia pahangi 
2010-05-22 | E-GEOD-14939 | biostudies-arrayexpress
MetabolomicsResolving coral photoacclimation dynamics through coupled photophysiological and metabolomic profiling
Corals continuously adjust to short term variation in light availability on shallow reefs. Long-term light alterations can also occur due to natural and anthropogenic stressors, as well as management interventions such as coral transplantation. Although short term photophysiological responses are re...
2019-04-11 | MTBLS768 | MetaboLights
TranscriptomicsMARS-seq Version 2
scRNA-seq procedure and analysis. ScRNA-seq was performed using the Massively Parallel Single-Cell RNA-sequencing technology (MARS-seq) as described by Jaitin et al., 2014 (PMID: 24531970) EpiSCs were seeded at ~6 x 103 cells/cm2 in 6-well cell-culture plates pre-coated with 15 µg/ml human Fibronec...
ORGANISM(S): Mus musculus 
2025-04-28 | E-MTAB-13660 | biostudies-arrayexpress
GenomicsWhole Genome Bisulfite Sequencing of CLDN6High vs CLDN6Low Sorted EpiSCs and APSD, and WT vs Pbx1-KO EpiSCs
The experiment was designed to assess the DNA methylation differences between CLDN6Low vs CLDN6High EpiSCs and APSD, as well as WT vs Pbx1-KO EpiSCs. Based on analysis of RNAseq data and GO, we narrowed down our focus to DNA methylation effects influencing lineage biases. We performed WGBS analysi...
ORGANISM(S): Mus musculus 
2025-04-28 | E-MTAB-13574 | biostudies-arrayexpress
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