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MetabolomicsMAVEN2: An Updated Open-Source Mass Spectrometry Exploration Platform

MAVEN, an open-source software program for analysis of LC-MS metabolomics data, was originally released in 2010. As mass spectrometry has advanced in the intervening years, MAVEN has been periodically updated to reflect this advancement. This manuscript describes a major update to the program, MA...

2024-07-22 | MTBLS3097 | MetaboLights
ProteomicsIn situ synthesis of peptide microarrays - shadow mask design [2]
An experiment was designed to use a computer program to create lithography masks using a pseudo-random pattern generator. The data in this file are results from immunosignaturing 8 different monoclonals using a 10,000 peptide random-sequence microarray. Peptides were synthesized by Sigma Aldrich, ...
ORGANISM(S): Mus musculus 
2014-01-16 | E-GEOD-50044 | biostudies-arrayexpress
ProteomicsIdentification of potential biomarkers for patients with neurodegenerative parkinsonian syndromes using serum cytokine microarray analysis; series 6
Background: Microarray technology may offer a new opportunity to gain insight into disease-specific global protein expression profiles. The present study was performed to apply a serum cytokine-array to screen for potential molecular biomarkers for Parkinson's disease (PD), multiple system atrophy (...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-32037 | biostudies-arrayexpress
ProteomicsIdentification of potential biomarkers for patients with neurodegenerative parkinsonian syndromes using serum cytokine microarray analysis; series 7
Background: Microarray technology may offer a new opportunity to gain insight into disease-specific global protein expression profiles. The present study was performed to apply a serum cytokine-array to screen for potential molecular biomarkers for Parkinson's disease (PD), multiple system atrophy (...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-32039 | biostudies-arrayexpress
ProteomicsIdentification of potential biomarkers for patients with neurodegenerative parkinsonian syndromes using serum cytokine microarray analysis; series 8
Background: Microarray technology may offer a new opportunity to gain insight into disease-specific global protein expression profiles. The present study was performed to apply a serum cytokine-array to screen for potential molecular biomarkers for Parkinson's disease (PD), multiple system atrophy (...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-32040 | biostudies-arrayexpress
ProteomicsIn situ synthesis of peptide microarrays - shadow mask design [1]
A computer program was used to create random amino acid sequences based on and restricted by physical shadow masks which will be used for lithography-based synthesis of peptides. The output from this algorithm was used to create peptides that were synthesized by Sigma Aldrich, and printed onto glas...
ORGANISM(S): Mus musculus 
2014-01-16 | E-GEOD-49217 | biostudies-arrayexpress
ProteomicsIdentification of differentially abundant proteins in glaucomatous and non-glaucomatous trabecular meshwork cell cultures using isobaric multiplexed quantitative proteomics
Glaucoma trabecular meshwork (GTM) cells cultured in vitro retain many characteristics of their in situ phenotype. We used isobaric labeling quantitative proteomics to identify proteins that were differentially regulated between glaucomatous and age-matched non-glaucomatous TM (NTM) cells. NTM (n=5)...
ORGANISM(S): Homo sapiens (Human) 
2026-04-07 | PXD066598 | Pride
Isobaric labeling Trabecular meshwork Glaucoma Mass spectrometry Human Cell culture Quantitative proteomics Extracellular matrix 
MetabolomicsProteomic and metabolomic profiling of acute and chronic stress events associated with military exercises.
By characterizing physiological changes that occur in warfighters during simulated combat, we can start to unravel the key biomolecular components that are linked to physical and cognitive performance. Viable field-based sensors for the warfighter must be rapid and noninvasive. In an effort to facil...
2023-12-05 | MTBLS5463 | MetaboLights
ProteomicsMicrobial alginate foraging is conserved in geographically and taxonomically distinct ruminant microbiomes
Saccharina latissima is a brown alga commonly found in the North Atlantic, Arctic and Pacific oceans. Alginate constitutes a substantial portion of the cell wall of S. latissima, and its digestion requires a specific set of enzymes, alginate lyases. We investigated if and how S. latissima is metabol...
ORGANISM(S): organismal metagenomes 
2026-04-16 | PXD059090 | Pride
TranscriptomicsNoggin vs BMP4 overexpression Epidermis
The study was performed to determine if there were alterations in the total RNA pool among the epidermal keratinocytes of K14 promotor-driven noggin overexpression compared with K14 promotor-driven BMP4 overexpression transgenic animals, which will directly relate to cellular chemistry and immune an...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-26231 | biostudies-arrayexpress
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