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The Experiment was performed to understand the changes in expression profile of enteric glia cells in vitro to specific cytokines. Enteric glia are crucial regulators of gastrointestinal motility and immunity; however, it is not fully understood what specific cytokines can elicit a response in enter...
ORGANISM(S): Mus musculus 
Proteins exhibit dynamics in their expression level in response to intracellular and extracellular signals. Regulation of protein turnover allows cells to rapidly and efficiently remodel their proteomes. It is known that proteins can show very different turnover rates in different tissue of the same...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-06-05 | PXD008596 | Pride
The objective of this study was to compare the transcriptomes of uninfected and canine distemper virus-infected Schwann cells, olfactory ensheating cells, central nervous system Schwann cell-like glia, and fibroblasts cultured under identical conditions in vitro.
ORGANISM(S): Canis familiaris 
To identify the gene expression profile of enteric glia and assess the transcriptional similarity between enteric and extraenteric glia, we performed RNA sequencing analysis on PLP1-expressing cells in the mouse intestine. This analysis shows that enteric glia are transcriptionally unique and distin...
ORGANISM(S): Mus musculus 
The Experiment was performed to understand the changes in expression profile of enteric glia cells in context of intestinal inflammation. Enteric glia are crucial regulators of gastrointestinal motility, however enteric glia alterations in IBD are poorly characterized. Acute T-cell activation rapidl...
ORGANISM(S): Mus musculus 
We produced bulk RNA sequencing data on Drosophila neurons, glia and hemocytes at embryonic and larval stages to extrapolate the most significant and specific features that identify a cell type as a whole. We also tracked changes in the expression in the two stages. We identified stable features tha...
ORGANISM(S): Drosophila melanogaster 
The adult central nervous system exhibits a limited capacity for neuronal regeneration, with retinal ganglion cells being particularly refractory to repair. Although this limitation is frequently attributed to neuron-intrinsic constraints, the contribution of the extracellular glial environment rema...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2026-09-02 | PXD082515 | Pride
These data serve as a reference transcriptomic profile for adult mouse retinal Muller glia. Retinas were dissociated into single cell suspensions and sorted into two fractions: a Muller glia-enriched fraction on the basis of Muller glia-specific tdTomato expression and a second fraction containing t...
ORGANISM(S): Mus musculus 
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