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TranscriptomicsDynamics of Nitrogen-regulated Gene Expression Reveals a Reciprocal Relationship between Cell Growth Rate and Nitrogen Catabolism
Cell growth rate is regulated in response to resource availability including the abundance, and molecular form, of essential nutrients. In the model eukaryotic cell, Saccharomyces cerevisiae (budding yeast), the molecular form of environmental nitrogen impacts both cell growth rate and mRNA express...
ORGANISM(S): Saccharomyces cerevisiae 
2014-05-05 | E-GEOD-57293 | biostudies-arrayexpress
TranscriptomicsEffects of human skeletal muscle fibroblast and stem cell media on cultured rat motor neuron cells
The study was designed to compare whether and how muscle fibroblasts (FIB) and muscle stem cells (MYO) interact with motor neurons. Moreover, we aimed to investigate whether muscle cells, isolated from lifelong exercisers, exerted a protective and supportive effect on motor neurons. These object...
ORGANISM(S): Rattus norvegicus 
2026-02-21 | E-MTAB-14399 | biostudies-arrayexpress
TranscriptomicsA chemical genetic approach identifies piperazine antipsychotics as promoters of CNS neurite growth on inhibitory substrates.
Injury to the central nervous system (CNS) may result in lifelong loss of function due, in part, to the regenerative failure of CNS neurons. Major barriers to regeneration faced by injured CNS neurons include inhibitory proteins derived from myelin and the astroglial scar. Previously, we described...
ORGANISM(S): Homo sapiens 
2012-04-29 | E-GEOD-34331 | biostudies-arrayexpress
TranscriptomicsExpression data from Epstein-Barr virus -positive and negative Akata Burkitt's Lymphoma Clones
Transition of Akata Burkitt lymphoma (BL) cells from a malignant to nonmalignant phenotype upon loss of Epstein-Barr virus (EBV) genomes in vitro is evidence for a viral contribution to tumor maintenance despite the tightly restricted pattern of EBV gene expression in BL. Akata cells retaining virus...
ORGANISM(S): Homo sapiens 
2010-01-19 | E-GEOD-19761 | biostudies-arrayexpress
UnknownInfluence of carbon to nitrogen ratios on soybean somatic embryo (cv. Jack) growth and composition.
Not available
S-EPMC3697947 | biostudies-literature
UnknownNpr2 inhibits TORC1 to prevent inappropriate utilization of glutamine for biosynthesis of nitrogen-containing metabolites.
Not available
S-EPMC4427238 | biostudies-literature
TranscriptomicsNext generation sequencing of Phaeodactylum tricornutum grown with and without nitrogen
We have done next generation sequencing of optically thin, exponentialy growing Phaeodactylum tricornutum cultures grown with and without nitrogen source to improve our undestanding of the pathways regulation under conditions that promote lipid accumulation (N-starvation). 3 biologically independent...
ORGANISM(S): Phaeodactylum tricornutum 
2015-01-02 | E-GEOD-56346 | biostudies-arrayexpress
UnknownDifferential substrate use in EGF- and oncogenic KRAS-stimulated human mammary epithelial cells.
Not available
S-EPMC8487438 | biostudies-literature
UnknownRole of GlnR in Controlling Expression of Nitrogen Metabolism Genes in Listeria monocytogenes.
Not available
S-EPMC7484187 | biostudies-literature
TranscriptomicsGene expression profiling of HD-MyZ Hodgkin lymphoma cell line after in vitro and in vivo treatment with perifosine in combination with sorafenib
Three HL cell lines (HD-MyZ, L-540 and HDLM-2) were used to investigate the effects of perifosine and sorafenib using in vitro assays analyzing cell growth, cell cycle distribution, gene expression profiling (GEP), and apoptosis. Western blotting (WB) experiments were performed to determine whether ...
ORGANISM(S): Homo sapiens 
2015-01-29 | E-GEOD-31058 | biostudies-arrayexpress
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