Glycan degradation

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MS:1001548 (1)
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CHEBI ID

CHEBI:17929 (4)
CHEBI:16335 (4)
CHEBI:17596 (4)
CHEBI:24266 (3)
CHEBI:28718 (3)
CHEBI:48430 (3)
CHEBI:26271 (3)
CHEBI:49033 (3)
CHEBI:22660 (3)
CHEBI:18186 (3)
CHEBI:16811 (3)
CHEBI:28300 (3)
CHEBI:18257 (3)
CHEBI:16708 (3)
CHEBI:17562 (3)
CHEBI:16750 (3)
CHEBI:16870 (3)
CHEBI:24898 (3)
CHEBI:25017 (3)
CHEBI:17268 (3)
CHEBI:28044 (3)
CHEBI:17568 (3)
CHEBI:18211 (3)
CHEBI:15891 (3)
CHEBI:16704 (3)
CHEBI:16027 (3)
CHEBI:15756 (3)
CHEBI:30769 (3)
CHEBI:33946 (2)
CHEBI:60647 (2)

Metabolite Name

Guanine (5)
Nicotinamide (4)
Adenosine (4)
L-Tryptophan (4)
Inosine (4)
Hydroxyprolyl-Tryptophan (3)
Quisqualic acid (3)
Phenylalanylphenylalanine (3)
Histidinol (3)
Indolepyruvate (3)
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N-Ethylglycine (3)
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Guanosine (3)
Sebacic Acid (3)
Uridine (3)
Pseudouridine (3)
Glycerophosphocholine (3)
8-Hydroxy-2-desoxyguanosine (2)
N-(R)-[2-(Hydroxyaminocarbonyl)methyl]-4-methylpentanoyl-L-t-butyl-alanyl-L-alanine, 2-aminoethyl Amide (2)
Pyropheophorbide-a (2)
Eliprodil (2)

First Public Date

2022 (8)
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2014 (5)
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2017 (3)
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2021 (2)
2016 (2)
2020 (1)
2019 (1)
2018 (1)
2011 (1)

Classification

bacteria (3)

Modification

15.994915 (1)
57.021464 (1)

Study type

Transcription profiling by array (64)
RNA-seq of coding RNA (19)
Unknown experiment type (8)
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Other (2)
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Release Date

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2015 (28)
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2000 (1)

Lab affiliation

Yazhouwan National Laboratory, Sanya 572024, China (3)
Department of Molecular & Integrative Physiology,University of Michigan Medical School, 5325 Brehm Tower, 1000 Wall St., Ann Arbor, MI, 48105 (2)
Department of Oral Biology and Pathology, Faculty of Odontology, Malmö University, Malmö, Sweden (2)
1Department of Chemistry and Sarafan Chem-H, Stanford University, Stanford, CA 94305, USA 2Howard Hughes Medical Institute, Stanford, CA 94305, USA (1)
BOKU University, Vienna, Austria (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Science4Life, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Biosciences Institute, Newcastle University, Newcastle, UK (1)
Center for Proteomics and Metabolomics, LUMC, The Netherlands (1)
Centre for Cardiovascular Biology and Disease Research, La Trobe Institute for Molecular Science and Department of Microbiology, Anatomy, Physiology and Pharmacology, School of Agriculture, Biomedicine and Environment, La Trobe University, Bundoora, VIC, Australia (1)
College of Plant Protection, Anhui Agricultural University (1)
Core Facility for Mass Spectrometry and Proteomics, Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany (1)
DTU BIOENGINEERING Department of Biotechnology and Biomedicine PCET-Protein Glycoscience and Biotechnology Technical University of Denmark 2800 Kgs. Lyngby (1)
Department of Chemistry, Stanford University (1)
Department of Clinical Chemistry and Transfusion Medicine at Institute of Biomedicine, SU Sahlgrenska 413 45 Gothenburg, Sweden (1)
Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK. (1)
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, United States (1)
Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden (1)
Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA (1)
Department of Molecular Ecology MPI for Marine Microbiology Celsiusstr. 1 D-28359 Bremen Germany (1)
Department of Neurology and Neurological Sciences, Stanford University, United States (1)
Department of Nutritional Sciences and Toxicology University of California, Berkeley (1)
Department of Oral Biology and Pathology, Faculty of Odontology, Malmo University, Malmo, Sweden (1)
Department of Oral Biology and Pathology, Faculty of Odontology, Malmö University, Malmö, Sweden Genovis AB, Kävlinge, Sweden (1)
Dept. of Molecular Cell Biology, Institute of Biochemistry of the Romanian Academy (IBRA) (1)
Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway (1)
Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne, UK. (1)
MPI for Marine Microbiology Celsiusstr. 1 D-28359 Bremen Germany (1)
Mucin Biology Groups Mass Spectrometry Laboratory, Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Sweden (1)
Mucin Biology Groups Mass Spectrometry Laboratory, Department of Medical Biochemistry and Cell Biology, Unuversity of Gothenburg, Sweden (1)
Pontificia Universidad Católica de Chile Department of Cellular and Molecular Biology Av. B. O’Higgins 340. Santiago, Chile Phone: 56-2-23541843 (1)

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Functional specialization of bacterial cellular and extracellular fractions contributes to polysaccharide degradation

Bacteroides thetaiotaomicron (Bt), a key commensal of the human gut microbiota, exhibits robust capacity to degrade dietary polysaccharides via carbohydrate-active enzymes (CAZymes). However, the exact spatial distribution and the functional coordination of these enzymes remain poor...

2026-03-27 | MTBLS14156 | MetaboLights

Glycan effect on Saccharolytic Human Distal Gut Symbiont, B. thetaiotaomicron

This SuperSeries is composed of the following subset Series: GSE11944: Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont GSE11953: Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF ...

ORGANISM(S): Bacteroides thetaiotaomicron

2008-11-20 | E-GEOD-11980 | biostudies-arrayexpress

Coordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont

Analysis of B. thetaiotaomicron trans-envelope signaling mutants in ECF-sigma factors, anti-sigma factors and SusC-like transporters. B. thetaiotaomicron mutants were transcriptionally profiled after growth in vitro in either minimal medium plus glucose or minimal medium plus neutral O-glycans

ORGANISM(S): Bacteroides thetaiotaomicron VPI-5482

2010-05-18 | E-GEOD-14592 | biostudies-arrayexpress

Inhibiting Glycan Degradation Prevents HIV-Induced Inflammaging and Cognitive Impairment

PRJNA1329335 | ENA

Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont

Gene expression profiles of Bacteroides thetaiotaomicron in vitro during growth on host mucosal polysaccharides as sole carbon sources. All substrates in this series are derived from porcine gastric mucin and include mucin O-glycans and glycosaminoglycans. Two different culture formats used: 800ml b...

ORGANISM(S): Bacteroides thetaiotaomicron

2008-11-20 | E-GEOD-11944 | biostudies-arrayexpress

Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF mutant

Growth of isogenic parent ('tdk strain'), 5xECF-sigma factor mutant and complemented mutant strain in the cecum of NMRI inbred mice fed a glycan-restricted, 'simple sugar' diet (35% each glucose and sucrose). Bacteria were collected from mouse distal gut 10 days after colonization. Experiment perfor...

ORGANISM(S): Bacteroides thetaiotaomicron

2008-11-20 | E-GEOD-11953 | biostudies-arrayexpress

Inhibiting Glycan Degradation Prevents HIV-Induced Inflammaging and Cognitive Impairment

Cognitive impairment is a frequent outcome of chronic viral infections linked to premature aging, including HIV. The mechanisms underlying this decline remain poorly understood. Here, we identify pro-inflammatory glycan degradation, characterized by loss of sialic acid and galactose, alterations tha...

ORGANISM(S): Mus musculus

2026-04-08 | GSE308269 | GEO

Glycan degradation promotes macroautophagy.

Not available

S-EPMC9245654 | biostudies-literature

Growth of B. thetaiotaomicron on purified host mucosal glycans and glycan fragments

Bacteroides thetaiotaomicron was grown and transcriptionally profiled on a number of different host mucosal glycans and their component mono- and disaccharides. Experiments are performed in biological duplicate (2 replicates per growth condition). All cultures were harvested at similar points in mid...

ORGANISM(S): Bacteroides thetaiotaomicron

2008-11-20 | E-GEOD-11962 | biostudies-arrayexpress

Efficient mucin O-glycan degradation by specific mucin degrading intestinal bacteria: towards understanding enzyme-glycan interactions.

Not available

S-EPMC12834350 | biostudies-literature

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