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TranscriptomicsGlobal profiling of gene expression during glycerol-induced spore formation in Myxococcus xanthus
Myxococcus xanthus is a gram negative rod-shaped delta proteobacterium that differentiates into environmentally resistant spores in response to starvation. Little is known about the sporulation mechanism in part because sporulation occurs in a subpopulation of cells undergoing a lenghtly complex mu...
ORGANISM(S): Myxococcus xanthus 
2010-05-06 | E-GEOD-17912 | biostudies-arrayexpress
TranscriptomicsRole of miRNAs in acute kidney injury recovery induced by mesenchymal stromal cells and derived extracellular vesicles.
Phenotypic changes induced by extracellular vesicles (EVs) have been implicated in the recovery of acute kidney injury (AKI) induced by mesenchymal stromal cells (MSCs). miRNAs are potential candidates for cell reprogramming towards a pro-regenerative phenotype. The aim of the present study was to e...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-59958 | biostudies-arrayexpress
TranscriptomicsProfiling of glycerol- and CTX-induced models of muscle regeneration in mice
Utilizing glycerol and cardiotoxin (CTX) injections in the tibialis anterior muscles of M. musculus provides models of skeletal muscle damages followed by skeletal muscle regeneration. In particular, glycerol-induced muscle regeneration is known to be associated with ectopic adipogenesis. We charact...
ORGANISM(S): Mus musculus 
2013-08-16 | E-GEOD-45577 | biostudies-arrayexpress
ProteomicsProteomic analysis of the bloodstream forms (slender, stumpy-QS, stumpy-Glyc, intermediate-Glyc) and procyclic forms of Trypanosoma brucei.
In the mammalian bloodstream, proliferative slender forms of T. brucei differentiate into cell cycle-arrested stumpy forms (stumpy-QS) via a quorum sensing mechanism triggered by high parasite density. This transition is thought to protect the host from excessive parasitaemia while preparing the par...
ORGANISM(S): Trypanosoma brucei 
2026-06-23 | PXD056405 | Pride
Glycerol-induced differentiation Label-free quantitative proteome analysis. Bloodstream forms Trypanosoma brucei Transmission 
TranscriptomicsGenomic characterization of osteoblastic differentiation of MC-3T3E1 cells
Gene expression analysis of murine MC3T3-E1 cells induced to undergo synchronized osteoblastic differentiation in vitro. MC3T3-E1 cells were cultured in vitro for up to 28 days in the presence of 8-glycerol phosphate and ascorbic acid to induce osteoblastic differentiation. Total RNA was isolated a...
ORGANISM(S): Mus musculus 
2012-06-27 | E-GEOD-30393 | biostudies-arrayexpress
TranscriptomicsAutotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice
Brown adipose tissue (BAT) is a thermogenic organ that dissipates stored energy as heat to maintain body temperature in infants and small mammals. This process may also provide protection from development of diet-induced obesity. We found that the bioactive lipid mediator lysophosphatidic acid (LP...
ORGANISM(S): Mus musculus 
2011-06-01 | E-GEOD-26442 | biostudies-arrayexpress
ProteomicsInvestigation of Oligodendrocyte Precursor Cell Differentiation by Quantitative Proteomics
Oligodendrocytes, the myelinating cells of the central nervous system, are essential for correct brain function. They originate from oligodendrocyte precursor cells (OPCs) through a differentiation process which is only incompletely understood and impaired in a variety of demyelinating diseases. Bet...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-06-21 | PXD012544 | Pride
Quantification Tmt labeling Oligodendrocytes Mass spectrometry Oligodendrocyte precursor cells 
TranscriptomicsTranscription profiling of human bone marrow derived mesenchymal stem stells during adipogensis, chondrogenesis and osteogenesis
Growth & differentiation mechanisms of Bone marrow derived mesenchymal stem cells.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-TABM-318 | biostudies-arrayexpress
TranscriptomicsGene expression in the Atlantic salmon adipose-derived stromal-vascular fraction during differentiation into adipocytes
Changes of gene expression in primary cell cultures of salmon adipose-derived stromal-vascular fraction were studied at six time-points that covered the key differentiation events: confluence, clonal expansion, determination and establishment of the mature adipocyte phenotype. Time-course experiment...
ORGANISM(S): Salmo salar 
2010-10-08 | E-GEOD-18389 | biostudies-arrayexpress
UnknownMelatonin improves muscle injury and differentiation by increasing Pax7 expression.
Not available
S-EPMC10008686 | biostudies-literature
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