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MetabolomicsLipidOA: A Machine-Learning and Prior-Knowledge-Based Tool for Structural Annotation of Glycerophospholipids
The Paternò-Büchi (PB) reaction is a carbon-carbon double bond (C═C)-specific derivatization reaction that can be used to pinpoint the location(s) of C═C(s) in unsaturated lipids and quantitate the location of isomers when coupled with tandem mass spectrometry (MS/MS). As the data of PB-MS/MS are in...
2022-11-23 | MTBLS6075 | MetaboLights
MetabolomicsDietary leucine restriction remodels the gut microbiota and serum glycerophospholipids to combat obesity

Abstract

Background The gut microbiota mediates dietary impacts on host metabolism, but the roles of specific amino acids remain elusive. We investigated the mechanism by which dietary leucine restriction combats obesity.

Methods Combining Mendelian randomization in humans with interv...

2025-11-07 | MTBLS13281 | MetaboLights
ProteomicsDandelion extract inhibits triple-negative breast cancer cell proliferation by interfering with glycerophospholipids and unsaturated fatty acids metabolism
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with limited treatment options and a poor prognosis. TNBC exists widely reprogrammed lipid metabolism, and its metabolic-associated proteins and oncometabolites are promising as potential therapeutic targets. Dandelion...
ORGANISM(S): Taraxacum mongolicum 
2022-10-14 | PXD035797 | Pride
Triple-negative breast cancer  dandelion extract  multi-omics  glycerophospholipid metabolism  choline kinase α. 
UnknownDistribution of Glycerophospholipids in the Adult Human Lens.
Not available
S-EPMC6315977 | biostudies-literature
UnknownCapture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry.
Not available
S-EPMC2822082 | biostudies-literature
UnknownDynamic modulations of sphingolipids and glycerophospholipids in COVID-19.
Not available
S-EPMC9549873 | biostudies-literature
UnknownPPM1J regulates meat quality feature and glycerophospholipids composition in broiler by modulating protein dephosphorylation.
Not available
S-EPMC11544016 | biostudies-literature
UnknownSelf-glycerophospholipids activate murine phospholipid-reactive T cells and inhibit iNKT cell activation by competing with ligands for CD1d loading.
Not available
S-EPMC6405219 | biostudies-literature
UnknownDandelion extract inhibits triple-negative breast cancer cell proliferation by interfering with glycerophospholipids and unsaturated fatty acids metabolism.
Not available
S-EPMC9486077 | biostudies-literature
UnknownA rapid ambient ionization-mass spectrometry approach to monitoring the relative abundance of isomeric glycerophospholipids.
Not available
S-EPMC4399504 | biostudies-literature
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