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TranscriptomicsCoordinate Regulation of Metabolites Glycosylation and Stress Hormones Biosynthesis by TT8 in Arabidopsis
Secondary metabolites play a key role in coordinating ecology and defense strategies of plants. Diversity of these metabolites arise by conjugation of core structures with diverse chemical moieties, such as sugars in glycosylation. Active pools of phytohormones, including those involved in plant str...
ORGANISM(S): Arabidopsis thaliana 
2016-07-20 | E-GEOD-59048 | biostudies-arrayexpress
TranscriptomicsH. pylori G27 HP0518 mutant showed greater motility
Helicobacter pylori is a human gastric pathogen associated with gastric and duodenal ulcers as well as specific gastric cancers. It is well-evidenced that motility is essential for this pathogen to colonize human gastric tissues. We found that the H. pylori G27 HP0518 mutant showed greater motility ...
ORGANISM(S): Helicobacter pylori 
2010-12-22 | E-GEOD-14752 | biostudies-arrayexpress
GenomicsDefective N-Glycosylation of IL6 Induces Metastasis and Tyrosine Kinase Inhibitor Resistance in Lung Cancer
Defective N-Glycosylation of IL6 Induces Metastasis and Tyrosine Kinase Inhibitor Resistance in Lung Cancer
PRJNA1123684 | ENA
TranscriptomicsGlycosylation regulates the stability of c-MYC
Tumorigenesis is characterised by changes in transcriptional regulation and the androgen receptor (AR) has been identified as a key driver in prostate cancer. In this study, we show that the hexosamine biosynthetic pathway (HBP) genes are overexpressed in clinical prostate cancer and androgen-regula...
ORGANISM(S): Homo sapiens 
2013-05-30 | E-GEOD-44624 | biostudies-arrayexpress
ProteomicsSecretory expression of mammalian NOTCH tandem epidermal growth factor-like repeats based on increased O-glycosylation
EGF domains of human NOTCH3 were prepared from HEK293T cells.
ORGANISM(S): Homo Sapiens (human) 
2024-07-27 | PXD035703 | JPOST Repository
TranscriptomicsGlycosylation change in mouse CD8 T cells during development
Dr. Jameson's research focus is on development and regulation of lymphocytes, especially T cells. Recent work has suggested that differential glycosylation effects the sensitivity of the T cell receptors and its coreceptors, suggesting that regulation of glycosylation may be a critical element in co...
ORGANISM(S): Mus musculus 
2010-12-11 | E-GEOD-26012 | biostudies-arrayexpress
GenomicsRNA sequencing/Gene expression studies of N-glycosylation inhibitors in diffuse lymphoma
RNA sequencing/Gene expression studies of N-glycosylation inhibitors in diffuse lymphoma
PRJNA875065 | ENA
ProteomicsO-linked Glycosylation of the SARS-CoV-2 Spike is Suppressed by Quaternary Structural Restraints
Understanding the glycosylation of envelope spike (S) protein of SARS-CoV-2 is important in defining the antigenic surface of this key viral target. However, the underlying protein architecture may significantly influence glycan occupancy and processing. There is, therefore, potential for different ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-07-28 | MSV000087897 | MassIVE
TranscriptomicsRNA sequencing/Gene expression studies of N-glycosylation inhibitors in diffuse lymphoma
We determined that N-linked glycosylation p[lays a role in oncogenic signaling in diffuse lymphoma. We sought to obtain gene expression data and gene signatures in diffuse lymphoma cells by examining changes in gene expression by RNA seq following treatment with the N-linked glycosylation inhibitor ...
ORGANISM(S): Homo sapiens 
2022-09-06 | GSE212337 | GEO
ProteomicsNascent glycoproteome reveal the suppressed expression of glycosylated LAMP2 in response to N-linked glycosylation inhibition
(1) Analysis of newly synthesized proteins under glycosylation inhibition (2) Analysis of newly synthesized glycoproteins during NGI-1 treatment
ORGANISM(S): Homo Sapiens 
2021-09-04 | PXD028212 |
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