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TranscriptomicsTranscription profiling of mouse colonic goblet cells deficient in Atg5
Purpose of this experiment was to gain insight into the transcriptional changes resulting from Atg5 deficiency in colonic goblet cells.
ORGANISM(S): Mus musculus 
2010-09-30 | E-TABM-815 | biostudies-arrayexpress
ProteomicsTrans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation
A key feature in intestinal immunity is the dynamic intestinal barrier, which separates the host from resident and pathogenic microbiota through a mucus gel impregnated with antimicrobial peptides. The mechanisms underlying the maintenance and function of this intestinal barrier are not completely ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-12-12 | MSV000090883 | MassIVE
ProteomicsIdentification of key pro-survival proteins in the isolated colonic goblet cells of Winnie, a murine model of spontaneous colitis
A proteomics comparison of goblet cell extracts prepared from control mice and animals expressing a misfolding mutant of Muc2, the major secretory product of goblet cells.
ORGANISM(S): Mus musculus (Mouse) 
2019-09-26 | PXD013166 | Pride
Quantitative proteomics  apoptosis  er stress  proliferation  ulcerative colitis  cancer 
TranscriptomicsTranscription profiling of mouse allergen-induced goblet cells
High numbers of goblet cells in airways contribute to the mucus obstruction characteristic of asthmatic airways. Allergen challenged mice exhibit robust expression of goblet cells within airway surface epithelium. This study looks at the temporal analysis of IL-13 exposed murine airways to elucida...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-481 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lung from individuals with airway hyperactivity and goblet cell metaplasia post-Sendai virus infection
Mice representing phenotypic extremes of airway hyperreactivity and goblet cell metaplasia post-Sendai virus infection were identified from a 500 mouse F2 cohort (CB6F2/J). Whole lung RNA from 3 mice at each extreme was analyzed via microarray for gene expression. Subsequent pairwise comparisons b...
ORGANISM(S): Mus musculus 
2007-07-06 | E-GEOD-3925 | biostudies-arrayexpress
GenomicsEffects of HSP90 inhibitors on airway goblet cell metaplasia
Effects of HSP90 inhibitors on airway goblet cell metaplasia
PRJNA480665 | ENA
ProteomicsIleum and colon goblet cell proteome
This study is a comparative proteomics study of FACS sorted Muc2 expressing and non expressing cells in mouse ileum and colon.
ORGANISM(S): Mus musculus (Mouse) 
2021-04-19 | PXD011527 | Pride
Ileum Proteomics Goblet cells Colon 
TranscriptomicsGene expression in small intestinal and colonic goblet cells from C57Bl/6 mice
Microarray analysis of goblet cells isolated from the small intestine or colon was completed to compare the cells between the two parts of the intestine. Total epithelium was isolated from the intestine by incubation in HBSS+0.05% EDTA at 37 C for 15 minutes. Goblet cells were isolated by FACS sorti...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-52418 | biostudies-arrayexpress
ProteomicsScreening of the transcriptome, mucinome, and O‐/N‐glycans of the intestinal goblet cell model HT29‐MTX during zinc deficiency
Zinc deficiency is a global health problem affecting approximately one billion people and is associated with serious health consequences, including impaired immune function and an increased susceptibility to infections and inflammation. It is also linked to disrupted intestinal homeostasis and a hig...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD080424 | Pride
Glycosylation Mucinome Goblet cell Zinc deficiency 
GenomicsGoblet Cell Adenocarcinoma Molecular Profiles
Goblet Cell Adenocarcinoma Molecular Profiles
PRJNA1101104 | ENA
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