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TranscriptomicsAnalysis of gene expression in JAK2 exon 12-mutant erythroblasts
For 13 patients with JAK2 exon 12-mutated polycythemia vera (PV), we compared genome-wide RNA profiles of JAK2-mutant (mutant) and wild-type erythroid colonies, grown from a single patient in the same culture plate. This paired approach controls for factors including age, gender, treatment, germline...
ORGANISM(S): Homo sapiens 
2015-10-04 | E-MTAB-3946 | biostudies-arrayexpress
UnknownHydroxycarbamide Plus Aspirin Versus Aspirin Alone in Patients With Essential Thrombocythemia Age 40 to 59 Years Without High-Risk Features.
Not available
S-EPMC6269131 | biostudies-literature
UnknownInfluence of structural characteristics on the binding of synthetic cannabinoids from the JWH family to the CB1 receptor: A computational study.
Not available
S-EPMC10841904 | biostudies-literature
TranscriptomicsBone marrow erythroblast arrays
JAK2V617F mutation is found in most patients with a myeloproliferative neoplasm (MPN), including polycythemia vera (PV), essential thrombocythemia (ET). We have demonstrated that heterozygous human JAK2V617F are associated with ET-like phenotypes while homozygosity for human JAK2V617F results in a ...
ORGANISM(S): Mus musculus 
2014-03-26 | E-MTAB-2427 | biostudies-arrayexpress
TranscriptomicsMutation Order Affects Tumor Evolution and Clinical Course of Disease
Background: Cancers result from accumulation of somatic mutations and their properties are thought to reflect the sum of these mutations. However, little is known about the consequences of altering the order of mutation acquisition. Methods: Mutation order was determined in myeloproliferative neopl...
ORGANISM(S): Homo sapiens 
2014-11-17 | E-MTAB-3086 | biostudies-arrayexpress
UnknownThird-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study.
Not available
S-EPMC6857629 | biostudies-literature
TranscriptomicsGenetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predispose to myeloproliferative neoplasms
Genome-wide association study of JAK2 V617F negative myeloproliferative neoplasms consisting of 524 cases at stage 1
ORGANISM(S): Homo sapiens 
2015-02-20 | E-MTAB-3340 | biostudies-arrayexpress
UnknownEffects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial.
Not available
S-EPMC6617509 | biostudies-literature
UnknownConstructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19.
Not available
S-EPMC9417284 | biostudies-literature
UnknownEffects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial.
Not available
S-EPMC7645733 | biostudies-literature
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