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UnknownFirst-in-Human Phase I Study of the Tamoxifen Metabolite Z-Endoxifen in Women With Endocrine-Refractory Metastatic Breast Cancer.
Not available
S-EPMC5648176 | biostudies-literature
TranscriptomicsTranscription profiling of mouse pre-implantation development over twelve time points from the germinal vesicle (GV) stage oocyte to the late (expanded) blastocyst
The goal of the experiments was to profile and analyze gene activity during murine pre-implantation development. Samples were collected at twelve time points from the germinal vesicle (GV) stage oocyte to the late (expanded) blastocyst.
ORGANISM(S): Mus musculus 
2004-02-19 | E-MEXP-51 | biostudies-arrayexpress
TranscriptomicsToxic effects of dietary methylmercury (MeHg) on juvenile rainbow trout
Juvenile rainbow trout were fed Biodiet starter (4% body weight per day) with MeHg added at 0, 0.5, 5 and 50 ppm for six weeks. Atomic absorption spectrometry was applied to measure the level of MeHg in the whole fish body. Trout at six weeks were sampled from each group for gene expression analysis...
ORGANISM(S): Oncorhynchus mykiss 
2013-06-01 | E-GEOD-32429 | biostudies-arrayexpress
ProteomicsKiP analysis of ER+ Breast Cancer
Endocrine therapies (ET) combined with CDK4/6 inhibition (CDK4/6i) is standard treatment for estrogen receptor-α-positive (ER+) breast cancer, however lethal drug resistance is common. Proteogenomic analyses of 22 ER+ breast cancer patient-derived xenografts (PDXs) demonstrated that PKMYT1, a WEE1 ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD050619 | Pride
Er+ breast cancer Pkmyt1 Endocrine therapy Cdk4/6 
ProteomicsNEOPALANA Proteomgenomic analysis
Neoadjuvant palbociclib and anastrozole (NeoPalAna) is a single-arm phase II clinical trial for patients with stage II/III ER+/HER2- breast cancer. Patients recieved Anastrozole for 4weeks followed by palbociclib. On day 15, patients were biopsied and Ki67% was determined. Patients with Ki67 >10% we...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD058250 | Pride
Estrogen receptor Endocrine therapy Breast cancer 
TranscriptomicsToxic effects of dietary methylmercury (MeHg) on young adult zebrafish
Three-month old zebrafish were fed Biodiet starter (4% body weight per day) with MeHg added at 0, 0.5, 5 and 50 ppm for six weeks. Atomic absorption spectrometry was applied to measure the level of MeHg in the whole fish body. Zebrafish at six weeks were sampled from each group for gene expression a...
ORGANISM(S): Danio rerio 
2013-06-01 | E-GEOD-32430 | biostudies-arrayexpress
GenomicsA Genome-Wide Association Study in Patients Experiencing Musculoskeletal Adverse Events on NCIC CTG Trial MA.27 Evaluating Aromatase Inhibitors as Adjuvant Therapy in Early Breast Cancer. A Collaboration Between the NIH Pharmacogenetics Research Network and the RIKEN Yokohama Institute Center for Genomic Medicine.

Source of Patients
The source of the patients for this genome-wide case control study was MA.27, which was conducted as a multi-cooperative group effort under the auspices of the NCI Breast Cancer Intergroup of North America. The NCIC Clinical Trials Group (CTG) serves as the co...

phs000210.v1.p1 | EGA
UnknownImpact of centre volume, surgeon volume, surgeon experience and geographic location on reoperation after intramedullary nailing of tibial shaft fractures
Not available
S-EPMC8410470 | biostudies-literature
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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