Sort   by:  
 Page size 
MetabolomicsTranscriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models

Microorganisms can adopt a quiescent physiological condition which acts as a survival strategy under unfavourable conditions. Quiescent cells are characterized by slow or non-proliferation and deep down-regulation of processes related to biosynthesis. Although quiescence has been described mostly...

2022-02-23 | MTBLS4046 | MetaboLights
ProteomicsAberrant neurodevelopment in human iPS cell-derived models of Alexander disease
Alexander disease (AxD) is a rare, severe neurodegenerative disorder caused by mutations in the glial fibrillary acidic protein (GFAP). While the exact disease mechanism remains unknown, existing studies suggest that the mutant GFAP influences many cellular processes, including cytoskeleton stabilit...
ORGANISM(S): Homo sapiens (Human) 
2024-09-09 | PXD048606 | Pride
Scrna-seq Alexander disease Gfap Ips cells Brain organoids 
MetabolomicsLaser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening

BACKGROUND: The introduction of high-risk human papillomavirus (hrHPV) testing as part of primary cervical screening is anticipated to improve sensitivity, but also the number of women who will screen positive. Reflex cytology is the preferred triage test in most settings but ha...

2022-02-15 | MTBLS1371 | MetaboLights
MetabolomicsRapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats
INTRODUCTION: Oats (Avena sativa L.) are a whole grain cereal recognised for their health benefits and which are cultivated largely in temperate regions providing both a source of food for humans and animals, as well as being used in cosmetics and as a potential treatment for a number of...
2020-06-11 | MTBLS804 | MetaboLights
ProteomicsGlioblastoma biomarkers in urinary extracellular vesicles reveal the potential for a ‘liquid gold’ biopsy
Background: Biomarkers that reflect glioblastoma tumour activity and treatment response are urgently needed to help guide clinical management, particularly for recurrent disease. As the urinary system is a major clearance route of circulating extracellular vesicles (EVs; 30-1000 nm nanoparticles) we...
ORGANISM(S): Homo sapiens (Human) 
2024-04-18 | PXD046511 | Pride
Proteomics Urine Dia Extracellular vesicles Glioblastoma Liquid biopsy 
UnknownRadiolysis-Driven Evolution of Gold Nanostructures - Model Verification by Scale Bridging In Situ Liquid-Phase Transmission Electron Microscopy and X-Ray Diffraction.
Not available
S-EPMC9443456 | biostudies-literature
UnknownMicrosphere Assisted Super-resolution Optical Imaging of Plasmonic Interaction between Gold Nanoparticles.
Not available
S-EPMC5653755 | biostudies-literature
UnknownGold Aerogels: Three-Dimensional Assembly of Nanoparticles and Their Use as Electrocatalytic Interfaces.
Not available
S-EPMC4768295 | biostudies-literature
UnknownMixture density networks for the indirect estimation of reference intervals.
Not available
S-EPMC9336034 | biostudies-literature
MetabolomicsCryogenic OrbiSIMS Localizes Semi-Volatile Molecules in Biological Tissues
OrbiSIMS is a recently developed instrument for label-free imaging of chemicals with micron spatial resolution and high mass resolution. We report a cryogenic workflow for OrbiSIMS (Cryo-OrbiSIMS) that improves chemical detection of lipids and other biomolecules in tissues. Cryo-OrbiSIMS boosts ioni...
2023-03-15 | MTBLS1873 | MetaboLights
Sort   by:  
 Page size