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TranscriptomicsMalaria primes the innate immune response due to IFNg induced enhancement of Toll-like receptor expression and function.
Patients with febrile malaria were recruited in order to determine Peripheral Blood Mononuclear Cell (PBMC) gene expression during malaria. Blood was harvested from patients during the acute phase of the illness, and then patients were given a curative regimen of antimalarials. Three to four weeks...
ORGANISM(S): Homo sapiens 
2009-03-13 | E-GEOD-15221 | biostudies-arrayexpress
TranscriptomicsATAC-seq of monocytes from patients before and after anti-malarial treatment
Patients received standardized coartem therapy. Briefly, each pill contains 20 mg of artemether and 120 mg of lumefantrine. The dose and total coarse of tablets is based on the patients body weight. Blood was drawn from patients prior to anti-malarial treatment (day 0) and after treatment (day42 for...
ORGANISM(S): Homo sapiens 
2022-04-24 | E-MTAB-11643 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of abx1 deletion or over expression in Streptococcus agalactiae and comparision with the effect of CovS and CovR deletion
Analysis of the impact of the abx1 deletion or over expression on S. agalactaie transcription profile and comparision to the effect of CovS and CovR deletion on transcriptomic profile. Some of the mutants are gene_knock_out mutants, but in other strains we have tested the over expression of the Abx1...
ORGANISM(S): Streptococcus agalactiae 
2013-02-26 | E-MEXP-3703 | biostudies-arrayexpress
TranscriptomicsNanostring profiling for immunologically relevant genes on RNA samples isolated from E. coli stimulated human FIP2 silenced macrophages
In order to investigate the importance of FIP2 on bacterially induced gene regulation, we performed a targeted transcriptome profiling for immunologically relevant genes on RNA samples isolated from E. coli stimulated human macrophages from 7 donor treated with non-targeting and FIP2 silencing siRNA...
ORGANISM(S): Homo sapiens 
2019-03-08 | E-MTAB-6790 | biostudies-arrayexpress
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