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MetabolomicsGolgi-IP, a tool for multimodal analysis of Golgi molecular content
The Golgi is a membrane-bound organelle that is essential for protein and lipid biosynthesis. It represents a central trafficking hub that sorts proteins and lipids to various destinations or for secretion from the cell. The Golgi has emerged as a docking platform for cellular signaling pathways inc...
2023-06-27 | MTBLS6511 | MetaboLights
ProteomicsGolgi-IP, a novel tool for multimodal analysis of Golgi molecular content
The Golgi plays an essential role in protein and lipid glycosylation. Golgi dysfunction is associated with a variety of diseases including cancer, neurodegeneration and cardiovascular disease. We developed a powerful immunoprecipitation technique to isolate the Golgi by tagging TMEM115. Golgi-immuno...
ORGANISM(S): Homo sapiens (Human) 
2023-04-24 | PXD038046 | Pride
Golgi-ip Proteomics Metabolomics Lipidomics Golgi apparatus 
UnknownGolgi-IP, a tool for multimodal analysis of Golgi molecular content.
Not available
S-EPMC10193996 | biostudies-literature
TranscriptomicsSLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis [ERIP_RNASeq]
The endoplasmic reticulum (ER) is the primary site of synthesis of secretory and membrane proteins, suggesting that specific mRNAs may be enriched at the ER surface. To characterize ER-associated transcripts, ER fractions were isolated using ER immunoprecipitation (ER-IP) and RNA was extracted from ...
ORGANISM(S): Homo sapiens 
2026-02-12 | GSE318826 | GEO
ProteomicsTBC1D23 mediates Golgi-specific LKB1 signaling
Identification of TBC1D23 interacting proteins by IP-MS; TBC1D23 preferentially regulates the phosphorylation of Golgi-localized proteins
ORGANISM(S): Homo Sapiens 
2023-03-13 | PXD040801 |
UnknownMetabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications.
Not available
S-EPMC3205354 | biostudies-literature
ProteomicsProteomic screen of PACS1 interactors in HCT116 cells
PACS1 syndrome is a neurodevelopmental disorder caused by a recurrent heterozygous missense mutation in PACS1 (p.R203W). We previously showed that PACS1R203W aberrantly potentiates HDAC6 activity, leading to Golgi fragmentation and neuronal deficits through an unresolved mechanism. To elucidate how ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD074970 | Pride
Pacs1 Pacs1 syndrome 
UnknownGolgi-situated endoplasmic reticulum α-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with γ-COP.
Not available
S-EPMC3623633 | biostudies-literature
ProteomicsIdentification of potential interactors of NKS1 and QUA1
Adjacent plant cells are connected by specialized cell wall regions, called middle lamellae, which influence critical agricultural characteristics, including fruit ripening and organ abscission. Middle lamellae are enriched in pectin polysaccharides, specifically homogalacturonan (HG). Pectins are m...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-03-20 | PXD047727 | Pride
Arabidopsis thaliana  na+ and k+-sensitive 1 (nks1)/elmo4  qua1  pectin 
ProteomicsT. gondi COG complex interactors LC-MS/MS
COG complexes are important proteins involved in the tethering and fusion of recycling vesicles in golgi cisternae. We investigated COG complexes in T. gondii and identified all 8 subunits to be present. We also looked into different interactors of COG and identified two novel proteins of interest. ...
ORGANISM(S): Toxoplasma gondii ME49 
2025-06-30 | PXD041887 | Pride
Cog complex Toxoplama 
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