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ProteomicsInnate immunocompetent iNSpheroids: A hiPSC-derived 3D model to study the central nervous system captures an early CNS response to rAAV
Gene therapies using adeno-associated viruses (AAVs) for central nervous system (CNS) disorders face challenges due to host immune responses not represented in classical preclinical models. Here, we present a human-induced pluripotent stem cell (hiPSC)-derived innate immunocompetent 3D CNS model tha...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD065639 | Pride
Gene therapy  neuroinflammation  cns models  glial cells 
UnknownEngineering defensin α-helix to produce high-affinity SARS-CoV-2 spike protein binding ligands.
Not available
S-EPMC9144876 | biostudies-literature
UnknownDeveloping a Nomogram for Prioritizing Hysteroscopy in Endometrial Cancer Diagnosis: A Case-Control Study.
Not available
S-EPMC10889308 | biostudies-literature
ProteomicsAddressing human astrogliosis in a hiPSC-derived 3D CNS model
Astrogliosis is an inflammatory process by which astrocytes undergo morphological, transcriptional, and functional changes that primarily contribute to tissue healing and restore CNS homeostasis as a response to neuroinflammation. However, excessive astrocyte activation causes neuronal death, immune...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD043835 | Pride
Astrogliosis  neuroinflammation  hipsc  3d culture  reactive astrocytes  stirred-tank bioreactors 
UnknownAnalysis of Immunological, Viral, Genetic, and Environmental Factors That Might Be Associated with Decreased Susceptibility to HIV Infection in Serodiscordant Couples in Florianopolis, Southern Brazil.
Not available
S-EPMC4651055 | biostudies-literature
UnknownSilver-Mediated Electrosynthesis of Substituted Isoquinolines via Cyclization of 2‑Ethynylbenzaldehydes.
Not available
S-EPMC12713483 | biostudies-literature
UnknownNon-equilibrium estimates of gene flow inferred from nuclear genealogies suggest that Iberian and North African wall lizards (Podarcis spp.) are an assemblage of incipient species.
Not available
S-EPMC2277379 | biostudies-literature
UnknownTime-Dependent Proteomic Signatures Associated with Embryogenic Callus Induction in Carica papaya L.
Not available
S-EPMC10675192 | biostudies-literature
Unknown(Re)Construction of the body of transgender women: daily search for (in)satisfaction and care?
Not available
S-EPMC9749498 | biostudies-literature
ProteomicsTime-dependent proteomic signatures associated with embry-ogenic callus induction in Carica papaya L.
The cost of Carica papaya production through seed-based propagation is increased by sex segregation, making in vitro techniques a more appealing option for clonal propagation. Inducing embryogenic callus with 2,4-dichlorophenoxyacetic acid (2,4-D) hold the potential to large-scale cloning, although ...
ORGANISM(S): Carica papaya 
2024-01-26 | PXD046521 | Pride
Bottom-up proteomics  carica papaya  embryogenic callus  somatic embryos  time-series analysis. 
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