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UnknownOverview of Systematic Reviews of Health Interventions for the Prevention and Treatment of Overweight and Obesity in Children.
Not available
S-EPMC9921486 | biostudies-literature
MetabolomicsPeripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a member of the beta-carbolines family with anti-depressant properties, i...
2023-05-26 | MTBLS7533 | MetaboLights
TranscriptomicsMolecular Signature of response and potential pathways related to resistance to the HSP90 inhibitor, 17-AAG, in breast cancer.
We have done transcriptional profiling of 17-AAG treated (24h, 48H) breast cancer cell lines to understand the mechanisms of the drug action and indicate novel set of pharmacodynamic biomarkers of the drug response as well as of resistance Two-condition experiment, Untreated vs. Treated sensitive c...
ORGANISM(S): Homo sapiens 
2010-10-11 | E-GEOD-23209 | biostudies-arrayexpress
UnknownAstrocytes Modulate Somatostatin Interneuron Signaling in the Visual Cortex.
Not available
S-EPMC9102536 | biostudies-literature
GenomicsGenome wide profiling of PAX8 binding stes in PCCL3 rat cells
Analysis of PAX8 binding sites by chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq) in PCCL3 rat cells. Results provide insight into the contribution of this regulatory factor to transcription genome-wide. We generate a genome wide map of PAX8 binding sites in PC...
ORGANISM(S): Rattus norvegicus 
2012-06-27 | E-GEOD-26871 | biostudies-arrayexpress
TranscriptomicsExpression and functional validation of new p38α transcriptional targets in tumorigenesis
p38α MAP kinase plays an important tumor suppressor role, which is mediated by both its negative effect on cell proliferation and its pro-apoptotic activity. Surprisingly, most tumor suppressor mechanisms coordinated by p38α have been reported to occur at the post- translational level. This contrast...
ORGANISM(S): Mus musculus 
2011-11-23 | E-GEOD-26762 | biostudies-arrayexpress
UnknownA Novel Introgression Line Library Derived from a Wild Melon Gives Insights into the Genetics of Melon Domestication, Uncovering New Genetic Variability Useful for Breeding.
Not available
S-EPMC10298652 | biostudies-literature
UnknownGABA tonic currents and glial cells are altered during epileptogenesis in a mouse model of Dravet syndrome.
Not available
S-EPMC9350930 | biostudies-literature
UnknownAstrocytes mediate in vivo cholinergic-induced synaptic plasticity.
Not available
S-EPMC3279365 | biostudies-literature
UnknownCardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome.
Not available
S-EPMC8614561 | biostudies-literature
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