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ProteomicsProtein profile of exosome derived from giant panda adipose-derived mesenchymal stem cells
Exosomes were extracted from adipose mesenchymal stem cells of Qnling giant pandas using ultracentrifugation. Proteomic techniques were applied to analyze the composition and function of ADMSC-EX.
ORGANISM(S): Ailuropoda melanoleuca (Giant panda) 
2025-05-26 | PXD059496 | Pride
Qinling giant pandas acmscs-ex 
ProteomicsProteomic Profiling of Inflammatory versus Noninflammatory Cartilage Regions in Knee Osteoarthritis Patients
This study performed data-independent acquisition (DIA)-based quantitative proteomic analysis on paired cartilage samples from inflammatory and noninflammatory regions of knee osteoarthritis (OA) patients. The objective was to characterize the proteomic alterations associated with cartilage inflamma...
ORGANISM(S): Homo Sapiens 
PXD078593 |
ProteomicsHypothalamic malate dehydrogenase 2 (MDH2) modulates systemic glucose metabolism through oxytocin-mediated thermogenesis
Bariatric surgery improves hyperglycemia in obesity and type 2 diabetes (T2D), yet its central mechanisms remain unclear. Through cerebrospinal fluid proteomic profiling of rats, we identify reduced central malate dehydrogenase 2 (MDH2) levels that correlate with surgery-induced restoration of normo...
ORGANISM(S): Rattus Norvegicus 
2025-12-19 | PXD072275 |
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