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TranscriptomicsRNA-seq for monitoring expression changes in absence of chromatin anchoring
RNA-seq for monitoring expression levels in mutants that do not anchor chromatin at the nuclear periphery. RNA-seq of depleted rRNA samples of early embryo extracts for three different genotypes: wild-type, cec-4_delta and met-2 set-25_delta_delta, in two independent biological replicas
ORGANISM(S): Caenorhabditis elegans 
2015-12-11 | E-GEOD-74067 | biostudies-arrayexpress
TranscriptomicsLead exposure induces changes in 5-hydroxymethylcytosine clusters in CpG islands in human embryonic stem cells and umbilical cord blood [ELEMENT]
Prenatal exposure to neurotoxicants such as lead (Pb) may cause stable changes in the DNA methylation (5mC) profile of the fetal genome. However few studies have examined its effect on the DNA de-methylation pathway, specifically the dynamic changes of the 5-hydroxymethylcytosine (5hmC) profile. The...
ORGANISM(S): Homo sapiens 
2015-06-08 | E-GEOD-69633 | biostudies-arrayexpress
ProteomicsIntracellular lipopolysaccharide regulates ER remodeling upon bacterial infection
The remodeling of endoplasmic reticulum (ER) is finely regulated by selective autophagy, known as ER-phagy. However, whether Gram-negative bacteria, which are known to manipulate the host membranous system, regulate ER-phagy remains elusive. We find that bacterial lipopolysaccharide (LPS) released u...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD053709 | Pride
Lipopolysaccharide Fam134b Er-phagy 
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