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UnknownStudy protocol for an observational cohort evaluating incidence and clinical relevance of perioperative elevation of high-sensitivity troponin I and N-terminal pro-brain natriuretic peptide in patients undergoing lung resection.

Introduction

Myocardial injury after non-cardiac surgery has been defined as myocardial injury due to ischaemia, with or without additional symptoms or ECG changes occurring during or within 30 days after non-cardiac surgery and mainly diagnosed based on elevated postoperative cardiac tropon...
S-EPMC9743392 | biostudies-literature
UnknownParkinson's Disease Gene Screening in Familial Cases from Central and South America.

Background

Parkinson's disease (PD) is the second most common neurodegenerative disease following Alzheimer's disease. Nearly 30 causative genes have been identified for PD and related disorders. However, most of these genes were identified in European-derived families, and little is known a...
S-EPMC11490405 | biostudies-literature
UnknownHuman IRF1 governs macrophagic IFN-γ immunity to mycobacteria.
Inborn errors of human IFN-γ-dependent macrophagic immunity underlie mycobacterial diseases, whereas inborn errors of IFN-α/β-dependent intrinsic immunity underlie viral diseases. Both types of IFNs induce the transcription factor IRF1. We describe unrelated children with inherited complete IRF1 def...
S-EPMC9907019 | biostudies-literature
UnknownReal world outcomes of momelotinib in myelofibrosis patients with anemia: results from the MOMGEMFIN study.
Not available
S-EPMC12006532 | biostudies-literature
UnknownValidation of the 'Test of the Adherence to Inhalers' (TAI) for Asthma and COPD Patients.

Background

To validate the 'Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma.

Methods

A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients wi...
S-EPMC4841905 | biostudies-literature
UnknownIncidence and clinical manifestations of giant cell arteritis in Spain: results of the ARTESER register.

Objective

This study aimed to estimate the incidence of giant cell arteritis (GCA) in Spain and to analyse its clinical manifestations, and distribution by age group, sex, geographical area and season.

Methods

We included all patients diagnosed with GCA between 1 June 2013 and 29 Marc...
S-EPMC10966818 | biostudies-literature
UnknownIdentification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study.

Background

The clinical presentation of COVID-19 in patients admitted to hospital is heterogeneous. We aimed to determine whether clinical phenotypes of patients with COVID-19 can be derived from clinical data, to assess the reproducibility of these phenotypes and correlation with prognosis,...
S-EPMC7906623 | biostudies-literature
UnknownDevelopment and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score.

Objective

To develop and validate a prediction model of mortality in patients with COVID-19 attending hospital emergency rooms.

Design

Multivariable prognostic prediction model.

Setting

127 Spanish hospitals.

Participants

Derivation (DC) and external validation (VC) coho...
S-EPMC7908055 | biostudies-literature
UnknownEffect of Direct Transportation to Thrombectomy-Capable Center vs Local Stroke Center on Neurological Outcomes in Patients With Suspected Large-Vessel Occlusion Stroke in Nonurban Areas: The RACECAT Randomized Clinical Trial.

Importance

In nonurban areas with limited access to thrombectomy-capable centers, optimal prehospital transport strategies in patients with suspected large-vessel occlusion stroke are unknown.

Objective

To determine whether, in nonurban areas, direct transport to a thrombectomy-capabl...
S-EPMC9073661 | biostudies-literature
UnknownInternational Impact of COVID-19 on the Diagnosis of Heart Disease.

Background

The coronavirus disease 2019 (COVID-19) pandemic has adversely affected diagnosis and treatment of noncommunicable diseases. Its effects on delivery of diagnostic care for cardiovascular disease, which remains the leading cause of death worldwide, have not been quantified.

Obje...

S-EPMC7836433 | biostudies-literature
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