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ProteomicsRBPMS mediates smooth muscle specific alternative splicing via oligomerization and modulation of trans splicing factor recruitment
RBPMS regulates alternative splicing decision via recruiting other trans factors. This experiment aims to investigate the interactome of Strep-II tagged recombinant RBPMS in Hela nuclear extract. The interactome of the full length protein is compared to the construct lacking the far C-terminal 20 am...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD037620 | Pride
Human  lc msms  rbpms  ap-ms: splicing factor  rbp 
ProteomicsRBPMS mediates smooth muscle specific alternative splicing via oligomerization and modulation of trans factor recruitment
RBPMS regulate splicing decisions by modulating the transcript-bound proteome. This experiment aims to investigate the proteome assembled on an experimental RNA, TM3 transcript, in human Hela nuclear extract under the various conditions, ± ATP and ± RBPMS. The model RNA is tethered on amylose bead v...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD037617 | Pride
Lc ms/ms Rna Alternative splicing factor Human 
TranscriptomicsTranscriptome profiling of dedifferentiating smooth muscle cells from mouse aorta and bladder
Smooth muscle cells (SMCs) are important in a number of physiological systems and organs, including the cardiovascular system. The hallmark property of differentiated SMCs is the ability to contract, but contractile SMCs themselves show a range of phenotypes allowing prolonged tonic contraction in v...
ORGANISM(S): Mus musculus 
2016-07-01 | E-MTAB-4841 | biostudies-arrayexpress
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