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TranscriptomicsGenome-wide identification of rat long non-coding RNAs
In the current study, we have focused on a distinct group of non-coding elements, lncRNA, and profiled renal tissues from three different inbred rat strains. We chose the three strains S, SHR and R for the main purpose of cataloging lncRNA annotations from the most widely used rat models of cardiov...
ORGANISM(S): Rattus norvegicus 
2014-12-10 | E-GEOD-58701 | biostudies-arrayexpress
TranscriptomicsGenome-wide identification of rat long non-coding RNAs (microarray)
In the current study, we have focused on a distinct group of non-coding elements, lncRNA, and profiled renal tissues from three different inbred rat strains. We chose the three strains S, SHR and R for the main purpose of cataloging lncRNA annotations from the most widely used rat models of cardiov...
ORGANISM(S): Rattus norvegicus 
2014-12-10 | E-GEOD-59165 | biostudies-arrayexpress
TranscriptomicsDEFINING A RAT BLOOD PRESSURE QUANTITATIVE TRAIT LOCUS TO A <81.8KB CONGENIC SEGMENT: COMPREHENSIVE SEQUENCING AND RENAL TRANSCRIPTOME ANALYSIS.
Evidence from multiple linkage and genome-wide association studies suggest that human chromosome 2 (HSA2) contains alleles that influence blood pressure (BP). Homologous to a large segment of HSA2 is rat chromosome 9 (RNO9), to which a BP quantitative trait locus (QTL) was previously mapped. The obj...
ORGANISM(S): Rattus norvegicus 
2010-07-15 | E-GEOD-22515 | biostudies-arrayexpress
TranscriptomicsImpaired endosomal recycling in proximal tubules is mechanistically linked to proteinuria
Through substitution mapping studies, we previously identified that a <330kb region from a rat strain with no renal pathology (the Lewis rat), which when introgressed onto the genetic background of a rat with renal disease (the Dahl Salt-sensitive (S) rat), caused an increase rather than the expecte...
ORGANISM(S): Rattus norvegicus 
2011-12-17 | E-GEOD-30770 | biostudies-arrayexpress
TranscriptomicsAnalysis of the placental tissue transcriptome from normal and testosterone treated rat pregnancy
Elevated testosterone levels increase maternal blood pressure and decrease uterine blood flow in pregnancy, resulting in abnormal perinatal outcomes. The placenta is the key in understanding the pathophysiological processes associated with pregnancy. The current study is designed to characterize the...
ORGANISM(S): Rattus norvegicus 
2015-04-20 | E-GEOD-61543 | biostudies-arrayexpress
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