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ProteomicsStructural and Functional Interrogation of Active Streptococcus pneumoniae Sortase A
Sortase A (SrtA) enzymes covalently anchor surface proteins to Gram-positive bacterial cell walls, promoting colonization and virulence. In Streptococcus pneumoniae, previous studies identified both a domain-swapped dimer and an active refolded monomer, but the active enzyme has not been characteriz...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2026-10-05 | PXD082607 | Pride
Enzyme Sortase-a  streptococcus pneumoniae  nmr  lc-ms/ms 
TranscriptomicsGene expression profiling of individual human oocytes and embryos
Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic ...
ORGANISM(S): Homo sapiens 
2013-12-13 | E-MEXP-3870 | biostudies-arrayexpress
UnknownPower Strokes in Molecular Motors: Predictive, Irrelevant, or Somewhere in Between?
Not available
S-EPMC11728019 | biostudies-literature
UnknownHome self-administration of intravenous antibiotics as part of an outpatient parenteral antibiotic therapy service: a qualitative study of the perspectives of patients who do not self-administer.
Not available
S-EPMC6347967 | biostudies-literature
TranscriptomicsTranscription profiling of Xenopus tropicalis tadpole tail tissue regeneration following removal
In this experiment, we show transcription profiling of the Xenopus tropicalis tadpole tail tissue regeneration following removal. The tail tissues include its spinal cord, notochord, muscle, and dorsal aorta. We characterized the early, intermediate, and late stages of Xenopus tropicalis tail regene...
ORGANISM(S): Xenopus tropicalis 
2010-10-01 | E-MEXP-2420 | biostudies-arrayexpress
UnknownRandomized Double-Blind Trial of Pregabalin Versus Placebo in Conjunction With Palliative Radiotherapy for Cancer-Induced Bone Pain.
Not available
S-EPMC5098845 | biostudies-literature
TranscriptomicsSRS endotype assignment of septic shock patients from the VANISH randomised trial
The aim of the experiment was to assign patients enrolled in the VANISH randomised trial to sepsis response signature (SRS) endotypes based on a previously published gene expression signature, in order to test for differential responses to treatment. VANISH was a double-blind randomised clinical tri...
ORGANISM(S): Homo sapiens 
2022-07-12 | E-MTAB-7581 | biostudies-arrayexpress
UnknownChair based exercise in community settings: a cluster randomised feasibility study.
Not available
S-EPMC5883353 | biostudies-literature
UnknownA phase 1 study of TRC102, an inhibitor of base excision repair, and pemetrexed in patients with advanced solid tumors.
Not available
S-EPMC6662598 | biostudies-literature
TranscriptomicsMicroarray transcriptomic profiling of patients with sepsis due to faecal peritonitis and pneumonia to identify shared and distinct aspects of the transcriptomic response (discovery cohort)
We assayed leukocyte global gene expression for a prospective validation cohort of 221 adult patients admitted to UK intensive care units with sepsis due to community acquired pneumonia or faecal peritonitis. 10 samples from patients scheduled for elective cardiac surgery were also assayed as non-se...
ORGANISM(S): Homo sapiens 
2017-05-01 | E-MTAB-5273 | biostudies-arrayexpress
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