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Proteomics2D-DIGE global protein profiling of alcohol-dependent mouse brain
Data analysis. Spot detection and matching were performed with a comparative cross analysis of all the gels using DeCyder software v.6.5 (GE Healthcare). 178 spots were selected based on 1.15-fold for protein ratio cut-off, allowing for the appearance of the spots in 23 out of 28 gels (69 out of 8...
ORGANISM(S): Mus musculus (Mouse) 
2014-07-28 | PXD000349 | Pride
Cie Mouse Brain Alcohol dependence Midbrain Cortex 2d-dige 
TranscriptomicsmicroRNA Expression based, Effects of Chronic Intermittent Ethanol paradigm on mouse brain
We analyzed cerebral cortices (CTX) and midbrains (MB) from male C57BL/6J mice subjected to a CIE, 2BC paradigm, which induces heavy drinking and represents one of the best available animal models for alcohol dependence and relapse drinking. Samples from CTX and MB of 21 mice: 7 Naïve, 7 Air-2BC, an...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-48576 | biostudies-arrayexpress
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