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NLRP3 inflammasome assembles in response to stress or danger signals and leads to unconventional secretion of proinflammatory IL-1. FADD is an NLRP3 inflammasome component. Here we found that classical NLRP3 inflammasome activation in human monocytes/macrophages induced FADD secretion, which require...
ORGANISM(S): Homo sapiens (Human) 
2019-02-28 | PXD008168 | Pride
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