Sort   by:  
 Page size 
TranscriptomicsDistinct gene signatures define pathogen- versus diet-induced atherosclerosis development
The goal of this study was to define gene expression profiles in aortic tissue in response to three pro-atherogenic stimuli at two time points. We identified gene expression profiles induced by oral P.gingivalis (Pg), intranasal C. pneumoniae (Cp), and Western diet (WD) at acute (1 day after last in...
ORGANISM(S): Mus musculus 
2015-01-06 | E-GEOD-60086 | biostudies-arrayexpress
TranscriptomicsNotch signaling-dependent gene expression in the developing mouse lung
Transcriptional profiling of Control and RbpjkCNULL lungs from E18.5. For microarray profiling, total RNA from E18.5 lungs was submitted for labeling and hybridization (Mouse Gene 1.0 ST Whole Genome Array, Affymetrix) to the Boston University Microarray Core facility. Clara cells (CCs) are a morph...
ORGANISM(S): Mus musculus 
2014-03-13 | E-GEOD-52926 | biostudies-arrayexpress
TranscriptomicsProfiling premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis
Lung squamous cell carcinoma (SCC) is thought to arise from premalignant lesions in the airway epithelium, therefore studying these lesions is critical for understanding lung carcinogenesis. We performed RNA sequencing on laser-microdissected representative cell populations along the SCC pathologica...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-49155 | biostudies-arrayexpress
TranscriptomicsEmergence of a developmental stage-dependent human liver disease signature demonstrated by directed differentiation of alpha-1 antitrypsin deficient iPS cells [HumanMethylation450]
We monitored 9 pluripotent stem cell lines across three time points of hepatic directed differentiation, representing 3 developmental stages: undifferentiated (T0), definitive endoderm (T5), and early hepatocyte (T24). ESCs (n=3) and patient-derived normal (n=3) or PiZZ (n=3) iPSCs were analyzed in ...
ORGANISM(S): Homo sapiens 
2015-04-15 | E-GEOD-66077 | biostudies-arrayexpress
TranscriptomicsEmergence of a developmental stage-dependent human liver disease signature demonstrated by directed differentiation of alpha-1 antitrypsin deficient iPS cells [miRNA-2_0]
We monitored 9 pluripotent stem cell lines across three time points of hepatic directed differentiation, representing 3 developmental stages: undifferentiated (T0), definitive endoderm (T5), and early hepatocyte (T24). ESCs (n=3) and patient-derived normal (n=3) or PiZZ (n=3) iPSCs were analyzed in ...
ORGANISM(S): Homo sapiens 
2015-04-15 | E-GEOD-66075 | biostudies-arrayexpress
TranscriptomicsEmergence of a developmental stage-dependent human liver disease signature demonstrated by directed differentiation of alpha-1 antitrypsin deficient iPS cells [HuGene-1_0-st]
We monitored 9 pluripotent stem cell lines across three time points of hepatic directed differentiation, representing 3 developmental stages: undifferentiated (T0), definitive endoderm (T5), and early hepatocyte (T24). ESCs (n=3) and patient-derived normal (n=3) or PiZZ (n=3) iPSCs were analyzed in ...
ORGANISM(S): Homo sapiens 
2015-04-15 | E-GEOD-66076 | biostudies-arrayexpress
TranscriptomicsEmergence of a developmental stage-dependent human liver disease signature demonstrated by directed differentiation of alpha-1 antitrypsin deficient iPS cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-04-15 | E-GEOD-66078 | biostudies-arrayexpress
TranscriptomicsA new approach for the study of lung smooth muscle phenotypes and its application in asthma
We developed a new method for the isolation of bronchial smooth muscle cells. This method is built upon a double fluorescent mouse SMA-GFP;NG2-DsRed and cell sorting. Using this method, we isolated bronchial smooth muscle cells from control and asthmatic C57BL/6J mice for gene profiling. Double fluo...
ORGANISM(S): Mus musculus 
2014-03-13 | E-GEOD-45723 | biostudies-arrayexpress
UnknownAzithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC7884931 | biostudies-literature
UnknownCasirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8830904 | biostudies-literature
Sort   by:  
 Page size