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Metabolomics1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty
Neutrophil function declines with age, but little is known about the changes in neutrophil metabolism that take place in robust older people and older people with frailty. We used 1H-NMR spectroscopy to investigate the metabolomic and lipidomic profiles of blood neutrophils from healthy y...
2026-03-26 | MTBLS6055 | MetaboLights
UnknownPrevalence of hypertension and other cardiovascular disease risk factors among university students from the National Polytechnic Institute of Cote d'Ivoire: A cross-sectional study.
Not available
S-EPMC9815567 | biostudies-literature
TranscriptomicsTranscription profiling of rat cardiac injury: a potential link to air pollution mortality?
Zinc (Zn) is a major elemental component of respirable ambient particulate matter (PM) detected often at alarming levels in urban air. Exposure to PM has been widely associated with increased cardiovascular morbidity and mortality, however, it is not known what components or sources of PM are causat...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-6541 | biostudies-arrayexpress
TranscriptomicsThe role of the Ras- and cAMP-signaling pathways in stress response and sterol biosynthesis in Cryptococcus neoformans
The cAMP-pathway plays a central role in regulation of growth, differentiation, and virulence of human pathogenic fungi, including Cryptococcus neoformans. Three major upstream signaling regulators of the adenylyl cyclase (Cac1), Ras, Aca1 (Adenylyl cyclase-associated protein 1) and G-alpha subunit ...
ORGANISM(S): Cryptococcus neoformans var. grubii H99 
2010-05-22 | E-GEOD-17338 | biostudies-arrayexpress
UnknownTreatment of pathophysiologic propagation outside of the pulmonary veins in retreatment of atrial fibrillation patients: RECOVER AF study.
Not available
S-EPMC10228624 | biostudies-literature
TranscriptomicsMolecular and Functional Characterization of the role of RNA silencing components in Cryptococcus neoformans
The RNA interference (RNAi) mediated by homology-dependent degradation of the target mRNA with small RNA molecules plays a key role in controlling transcription and translation processes in a number of eukaryotic organisms. The RNAi machinery is also evolutionarily conserved in a wide variety of fun...
ORGANISM(S): Cryptococcus neoformans var. grubii H99 
2010-05-01 | E-GEOD-21178 | biostudies-arrayexpress
UnknownCritically Ill Adults With Coronavirus Disease 2019 in New Orleans and Care With an Evidence-Based Protocol.
Not available
S-EPMC7487861 | biostudies-literature
TranscriptomicsIdentification of Sleep Regulatory Genes in Flies Mutant for the Clock Gene cycle
Extended periods of waking result in physiological impairments in humans, rats, and flies. Sleep homeostasis, the increase in sleep observed following sleep loss, is believed to counter the negative effects of prolonged waking by restoring vital biological processes that are degraded during sleep de...
ORGANISM(S): Drosophila melanogaster 
2014-04-15 | E-GEOD-18550 | biostudies-arrayexpress
TranscriptomicsCharacterization of the transcriptional heterogeneity present within the rat lymphatic and blood vasculatures
The goal and objective of this study was to identify the transcriptional profiles differentiating the artery, vein, and lymphatic lineages in the adult rat vasculature with particular emphasis on the unique elements of the collecting lymphatic vessel transcriptome. A 2 x 3 experimental design was ut...
ORGANISM(S): Rattus norvegicus 
2012-06-22 | E-GEOD-17015 | biostudies-arrayexpress
TranscriptomicsComparison of rat thoracic duct to vena cava
While blood vessels have muscular walls that undergo tonic contractions to alter vascular resistance and, thus, control blood flow, lymphatics at the level of the collecting vessels and higher have muscular walls capable of rapid phasic contractions that generate lymph flow in addition to tonic cont...
ORGANISM(S): Rattus norvegicus 
2010-05-15 | E-GEOD-7221 | biostudies-arrayexpress
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