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Strain GS115 transformed with the empty vector pGAPHIS (a histidine prototrophic isogenic strain of GS115) was compared to Strain GS115 HAC1, constitutively overproducing the activated form of S. cerevisiae Hac1
ORGANISM(S): Pichia pastoris 
Experiment aims to induce unfolded protein response in Pichia pastoris, set-up was chosen to be comparable results to DTT experiment.
ORGANISM(S): Pichia pastoris 
The effect of oxygen availability on recombinant protein production in Pichia pastoris
ORGANISM(S): Pichia pastoris 
Pichia pastoris was grown in carbon limited chemostat cultures on mineral medium with glucose as carbon source. 3 different osmolarities were selected (140, 850, 1400mOsmol kg-1). Samples were taken at steady-state, thus the effect of osmolarity in adapted cells was monitored.
ORGANISM(S): Pichia pastoris 
Sohn2010 - Genome-scale metabolic network of Pichia pastoris (PpaMBEL1254) This model is described in the article: Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production. Sohn SB, Graf AB, Kim ...
2015-07-30 | MODEL1507180050 | BioModels
Advanced colon cancer is characterized by drug resistance and a poor prognosis. In these patients tumor-propagating cells appear to be largely resistant against various targeted drugs including ErbB-inhibitors. The cell surface antigen prominin-1 (CD133) has recently been identified as a potential m...
ORGANISM(S): Homo sapiens 
Comparison of transcription profile of Pichia pastoris cells grown on Glucose medium with Pichia pastoris cells grown on Methanol/Glycerol medium, the fermentations were done in a chemostat. 2 color experiment in reference design. Pichia pastoris reference mix [mixed pool of Pichia pastoris cells sa...
ORGANISM(S): Komagataella pastoris CBS 7435 
Mature microRNA levels were analyzed in 4 producing CHO cell lines expressing 2 structurally different recombinant proteins at low and high level as well as in 1 non-producing CHO cell line. The goal was to identify microRNAs that are involved in heterologous protein formation and secretion. 5 recom...
ORGANISM(S): Cricetulus griseus 
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