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UnknownThe New Youngest Case of Grange Syndrome with a Novel Biallelic Pathogenic Variant in YY1AP1.
Not available
S-EPMC10267489 | biostudies-literature
TranscriptomicsExpression data from mouse perigonadal white adipose tissue - various mutant conditions [gene-level analysis]
Progerin-expressing mice (HGPS-like) demonstrated increased energy metabolism and lipodystrophy. Increased mitochondrial biogenesis was found in adipose tissue from HGPS-like mice, whereas lamin C-only mice had fewer mitochondria. Thus we analyse which molecular pathways mediated the changes in adip...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-51202 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse perigonadal white adipose tissue - various mutant conditions [exon-level analysis]
Progerin-expressing mice (HGPS-like) demonstrated increased energy metabolism and lipodystrophy. Increased mitochondrial biogenesis was found in adipose tissue from HGPS-like mice, whereas lamin C-only mice had fewer mitochondria. Thus we analyse which molecular pathways mediated the changes in adip...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-51203 | biostudies-arrayexpress
UnknownCrucial Role of the C-Terminal Domain of Hfq Protein in Genomic Instability.
Not available
S-EPMC7603069 | biostudies-literature
UnknownEnantioselective construction of C-chiral allylic sulfilimines via the iridium-catalyzed allylic amination with S,S-diphenylsulfilimine: asymmetric synthesis of primary allylic amines.
Not available
S-EPMC5592745 | biostudies-literature
UnknownFull adoption of the most effective strategies to mitigate methane emissions by ruminants can help meet the 1.5 °C target by 2030 but not 2050.
Not available
S-EPMC9171756 | biostudies-literature
UnknownYeast lacking the sterol C-5 desaturase Erg3 are tolerant to the anti-inflammatory triterpenoid saponin escin.
Not available
S-EPMC10442444 | biostudies-literature
TranscriptomicsABT-737 treatment induces regulation and activation of pathways implicated in cell survival, proliferation and stem cells in treated AML mice survival, proliferation and stem cells in treated AML mice
Myelodysplastic syndrome (MDS) transforms into an acute myelogenous leukemia (AML) with associated increased bone marrow blast infiltration. Using a transgenic mouse model, MRP8[NRASD12/hBCL-2], in which the NRAS:BCL-2 complex at the mitochondria induces MDS progressing to AML with dysplastic featur...
ORGANISM(S): Mus musculus 
2013-11-06 | E-GEOD-48601 | biostudies-arrayexpress
TranscriptomicsHuman induced pluripotent stem cells reveal early developmental molecular correlates with a probable Leber congenital amaurosis type I
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43946 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of human iPSC-derived Retinal Pigmented Epithelial (RPE) cells from LCA patients and unaffected persons
Our purpose was to investigate genes and molecular mechanisms involved in patients with Leber congenital amaurosis (LCA). Fibroblasts from two unrelated clinically-identified patients (Coriell) were reprogrammed to pluripotency by retroviral transduction. These human induced Pluripotent Stem Cells (...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43926 | biostudies-arrayexpress
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