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TranscriptomicsComparison of the effects of GMCSF, IL-4 and 15kDa Granulysin on elutriated monocytes: a 48 hour time point analysis
Gene expression profiling of elutriated monocytes cultured for 48 hours in RPMI-1640, 10% AB plamsa and one of the following: GMCSF (56IU/ml), IL-4 (2000 IU/ml), 15 kDa Granulysin (10 nM) Sources tested: monocytes form 3 donors tested at time 0, 4 hours, 12 hours, 24 hours, 48 hours 5 time points we...
ORGANISM(S): Homo sapiens 
2012-05-18 | E-GEOD-35304 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis patients blister cells from skin lesions reveals these consist of cytotoxic T cells annd NK cells
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis; (TEN) are life-threatening adverse drug reactions characterized; by massive epidermal necrosis, in which the specific danger; signals involved remain unclear. Here we show that blister; cells from skin lesions of SJS-TEN primarily consis...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-13727 | biostudies-arrayexpress
UnknownAntimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin.
Not available
S-EPMC4898823 | biostudies-literature
UnknownGranulysin: killer lymphocyte safeguard against microbes.
Not available
S-EPMC6800608 | biostudies-literature
GenomicsCD127+CD94+ innate lymphoid cells expanded in Crohn’s disease patients highly express granulysin and perforin
CD127+CD94+ innate lymphoid cells expanded in Crohn’s disease patients highly express granulysin and perforin
PRJNA726520 | ENA
Unknown15 kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity.
Not available
S-EPMC3370151 | biostudies-literature
UnknownConserved structure and function in the granulysin and NK-lysin peptide family.
Not available
S-EPMC1230960 | biostudies-literature
UnknownGRANULYSIN PEPTIDE AND GENE POLYMORPHISM IN THE PATHOGENESIS OF HASHIMOTO THYROIDITIS.
Not available
S-EPMC9867818 | biostudies-literature
UnknownGranulysin delivered by cytotoxic cells damages endoplasmic reticulum and activates caspase-7 in target cells.
Not available
S-EPMC6959523 | biostudies-literature
UnknownGranulysin as a novel factor for the prognosis of the clinical course of chickenpox.
Not available
S-EPMC9184931 | biostudies-literature
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