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TranscriptomicsEpigenetic profiling in CD4 and CD8 T cells from Graves disease patients reveals changes in genes associated with T cell receptor signaling
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-11-06 | E-GEOD-71957 | biostudies-arrayexpress
TranscriptomicsEpigenetic profiling in CD4 and CD8 T cells from Graves’ disease patients reveals changes in genes associated with T cell receptor signaling [methylation]
In Graves’ disease (GD), a combination of genetic, epigenetic and environmental factors causes an autoimmune response to the thyroid gland, characterized by lymphocytic infiltrations and autoantibodies targeting the thyroid stimulating hormone receptor (TSHR) and other thyroid antigens. To identif...
ORGANISM(S): Homo sapiens 
2015-11-06 | E-GEOD-71955 | biostudies-arrayexpress
TranscriptomicsGenetically-driven target tissue over-expression of CD40: A novel mechanism in autoimmune disease
The CD40 gene, an important immune regulatory gene, is also expressed and functional on non-myeloid derived cells, many of which are targets for tissue specific autoimmune diseases, including d thyroid follicular cells in Graves’ disease (GD). Whether target tissue CD40 expression plays a role in au...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-39081 | biostudies-arrayexpress
ProteomicsMablango_ClpP_HYTANE_P124_Lumos
This dataset consists of 6 raw MS files, acquired on Thermo Fusion Lumos mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by Keith Wong. Sample processing and mass spectrometry acquisition was performed by Cassandra Wong. Data analysis was performed by Cassandra...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-13 | MSV000089642 | MassIVE
TranscriptomicsGene expression changes upon knockdown or over-expression of the ETS gene ETV4 in prostate cancer cell lines
Chromosomal abnormalities that give rise to elevated expression levels of the ETS genes ETV1, ETV4, ETV5, or ERG are prevalent in prostate cancer, but the function of these transcription factors in carcinogenesis is not clear. Previous work implicates ERG, ETV1, and ETV5 as regulators of invasive gr...
ORGANISM(S): Homo sapiens 
2011-03-24 | E-GEOD-21209 | biostudies-arrayexpress
UnknownThe influence of sociodemographic factors on COVID-19 vaccine certificate acceptance: A cross-sectional study.
Not available
S-EPMC10259333 | biostudies-literature
TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [mRNA]
The capacity to sense and transduce temperature signals pervades all aspects of biology, and temperature exerts powerful control over the development and virulence of diverse pathogens. In the leading fungal pathogen of humans, Candida albicans, temperature has a profound impact on morphogenesis, a ...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34255 | biostudies-arrayexpress
TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise
This SuperSeries is composed of the following subset Series: GSE34255: Pho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [mRNA] GSE34938: Pho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevate...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34939 | biostudies-arrayexpress
UnknownDiscovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia.
Not available
S-EPMC8594913 | biostudies-literature
UnknownInsights into hominid evolution from the gorilla genome sequence.
Not available
S-EPMC3303130 | biostudies-literature
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