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MetabolomicsMetabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice
It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase 5 gene, Fmo5, slows metabolic ageing via pleiotropic effects. We have now used an NMR-based metabonomics approach to study the effects of ageing directly on the metabolic profiles of urine and plasma from male,...
2018-06-20 | MTBLS667 | MetaboLights
UnknownGenomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting.
Not available
S-EPMC5437524 | biostudies-literature
UnknownThe effect of Apolipoprotein E4 on cognitive function in Parkinson's disease: A structural MRI study in the PPMI cohort.
Not available
S-EPMC12818682 | biostudies-literature
UnknownDetectable ctDNA at the time of treatment cessation of ipilimumab and nivolumab for toxicity predicts disease progression in advanced melanoma patients.
Not available
S-EPMC10766351 | biostudies-literature
UnknownA spatio-temporal atlas of the developing fetal brain with spina bifida aperta.
Not available
S-EPMC10445840 | biostudies-literature
UnknownTaxonomical review of Prosymnaangolensis Boulenger, 1915 (Elapoidea, Prosymnidae) with the description of two new species.
Not available
S-EPMC9848606 | biostudies-literature
TranscriptomicsTranscriptional response to drug-induced oligomerization of the AIM2-like receptors IFI16, PYHIN1, and MNDA.
We explored ALR function in a ligand-independent manner using a drug-inducible dimerization system in which ALRs were tagged with two FV domains that rapidly oligomerize upon addition of the drug AP1 We found that oligomerization of IFI16, PYHIN1, or MNDA did not result in any significant gene expre...
ORGANISM(S): Homo sapiens 
2016-05-31 | E-GEOD-80598 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human cell lines to identify cAMP-response element binding protein (CREB) binding sites.
Hormones and nutrients often induce genetic programs via signaling pathways that interface with gene-specific activators. Activation of the cAMP pathway, for example, stimulates cellular gene expression by means of the PKA-mediated phosphorylation of cAMP-response element binding protein (CREB) at S...
ORGANISM(S): Homo sapiens 
2006-05-09 | E-WMIT-11 | biostudies-arrayexpress
UnknownAugmenting Mental Health Support for Patients Accessing Different Degrees of Formal Psychiatric Care through a Supportive Text Messaging Program: Protocol for a Randomized Controlled Trial.
Not available
S-EPMC9959317 | biostudies-literature
UnknownAssociation between VTE and antibiotic prophylaxis guideline compliance and patient-reported outcomes after total hip and knee arthroplasty: an observational study.
Not available
S-EPMC9556685 | biostudies-literature
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