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This study employed metabolomic profiling technologies, to identify metabolites (small molecules) in blood which are found at different levels in vaccinated compared to non-vaccinated animals exposed to virus.
2018-07-13 | MTBLS456 | MetaboLights
The proper balance of excitatory and inhibitory neurons is crucial to normal processing of somatosensory information in the dorsal spinal cord. Two neural basic helix-loop-helix transcription factors, Ascl1 and Ptf1a, are essential for generating the correct number and sub-type of neurons in multipl...
ORGANISM(S): Mus musculus 
Chronic alcohol consumption can lead to alchohol-related brain damage (ARBD). Despite the well known acute effects of alcohol the mechanism responsible for chronic brain damage is largely unknown. Pathologically the major change is the loss of white matter while neuronal loss is mild and restricted ...
ORGANISM(S): Homo sapiens 
The proper balance of excitatory and inhibitory neurons is crucial to normal processing of somatosensory information in the dorsal spinal cord. Two neural basic helix-loop-helix transcription factors, Ascl1 and Ptf1a, are essential for generating the correct number and sub-type of neurons in multipl...
ORGANISM(S): Mus musculus 
Proctor2007 - Age related decline of proteolysis, ubiquitin-proteome system This is a stochastic model of the ubiquitin-proteasome system for a generic pool of native proteins (NatP), which have a half-life of about 10 hours under normal conditions. It is assumed that these ...
2024-09-02 | BIOMD0000000105 | BioModels
Array comparative genomic hybridization characterization and comparison of cell lines from 9 different cancer tissue of origin types (Breast, Central Nervous System, Colon, Leukemia, Melanoma, Non-Small Cell Lung, Ovarian, Prostate, Renal) from NCI-60 panel.
ORGANISM(S): Homo sapiens 
In our attempts to profile different regulators of the WNT/b-catenin transcriptional complex, CUT&RUN failed to produce consistent binding patterns of the non-DNA-binding b-catenin. We developed a modified CUT&RUN protocol, which we refer to as LoV-U (Low Volume and Urea), that enables the generatio...
ORGANISM(S): Mus musculus 
The goal of this study is to investigate the biological role of the podocyte-specific long non-coding RNA Wt1os (human ortholog WT1-AS) and its contribution to glomerular health and disease. The experimental workflow integrates both in vivo and cell culture approaches. We generated a Wt1os loss-of-f...
ORGANISM(S): Mus musculus 
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