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TranscriptomicsGene expression profiles of effector T cells
This SuperSeries is composed of the following subset Series: GSE29606: Gene expression profiles of effector T cells induced by mTOR inhibition GSE29607: Comparison of gene expression profiles of effector T cells from leptin-receptor-deficient mice and wild type mice Refer to individual Series
ORGANISM(S): Mus musculus 
2012-09-05 | E-GEOD-29608 | biostudies-arrayexpress
TranscriptomicsDNA-METHYLATION - Integrative multi-omics survey of effects carbon-based engineered nanomaterials on lung derived cell-lines
In this study we exposed three human lung derived cell lines to sublethal dosages of nanomaterials for a limited amount of time. For the first time, we assessed the simultaneous effects of nanomaterials exposure on three distinct molecular layers along with their interactions in the determination of...
ORGANISM(S): Homo sapiens 
2018-05-19 | E-MTAB-6397 | biostudies-arrayexpress
TranscriptomicsHuman bone marrow mesenchymal stem cells, young vs. old donors, early vs. late passages
Mesenchymal stem/stromal cells (MSCs) with immunosuppressive properties are increasingly used in advanced cellular therapies. Since the clinical use of hMSCs demands sequential cell expansions, we studied the effect of cell doublings on the phospholipid profile as well as functionality of human bone...
ORGANISM(S): Homo sapiens 
2013-04-05 | E-GEOD-39035 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profiles of effector T cells from leptin-receptor-deficient mice and wild type mice
We have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed during leptin receptor deficiency, which is partly responsible for the inhibition of T cell effector functions. Mouse CD4+CD25- T cells were purified from leptin-receptor-...
ORGANISM(S): Mus musculus 
2012-09-05 | E-GEOD-29607 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of effector T cells induced by mTOR inhibition
To further develop our gene expression approach to treatment of autoimmunity, we have employed whole genome microarray expression profiling as a discovery platform to identify genes differentially expressed upon immunosuppressor treatment responsible for inhibition of T cell effector functions. Huma...
ORGANISM(S): Homo sapiens 
2012-09-05 | E-GEOD-29606 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human epithelial cell line (HL) infected with Chlamydia pneumoniae
Transcriptional profiling of human epithelial cell line (HL) infected with Chlamydia penumoniae compared to control cells at time points 12h, 24h, 48h, 72h after the infection. Experiment Overall Design: Two-condition experiment over the time. Biological replicates: 2 infected, 2 controls at each ti...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7246 | biostudies-arrayexpress
TranscriptomicsMRNA-Integrative multi-omics survey of effects carbon-based engineered nanomaterials on lung derived cell-lines
In this study we exposed three human lung derived cell lines to sublethal dosages of nanomaterials for a limited amount of time. For the first time, we assessed the simultaneous effects of nanomaterials exposure on three distinct molecular layers along with their interactions in the determination of...
ORGANISM(S): Homo sapiens 
2018-05-19 | E-MTAB-6396 | biostudies-arrayexpress
TranscriptomicsMIRNA - Integrative multi-omics survey of effects carbon-based engineered nanomaterials on lung derived cell-lines
In this study we exposed three human lung derived cell lines to sublethal dosages of nanomaterials for a limited amount of time. For the first time, we assessed the simultaneous effects of nanomaterials exposure on three distinct molecular layers along with their interactions in the determination of...
ORGANISM(S): Homo sapiens 
2018-05-19 | E-MTAB-6406 | biostudies-arrayexpress
TranscriptomicsGene expression profile of the SV40-immortalized human corneal epithelial cells
Microarray was used to study global gene expression of a cell culture model based on SV40-immortalized human corneal epithelial (iHCE) cells. The gene expression profile of the cell line was compared to the normal human corneal epithelium. Affymetrix HG-U133A GeneChips® were used for microarray exp...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-22539 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profile in embryonic mesencephalon and neuronal primary cultures
In the mammalian central nervous system (CNS) an important contingent of dopaminergic neurons are localized in the substantia nigra and in the ventral tegmental area of the ventral midbrain. They constitute an anatomically and functionally heterogeneous group of cells involved in a variety of regula...
ORGANISM(S): Rattus norvegicus 
2009-05-10 | E-GEOD-15920 | biostudies-arrayexpress
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