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ProteomicsCocaine and Environmental Enrichment Proteomics Study of Rat Nucleus Accumbens
Prior research demonstrated that environmental enrichment creates individual differences in behavior leading to a protective addiction phenotype in rats. Understanding the mechanisms underlying this phenotype will guide selection of targets for much-needed novel pharmacotherapeutics. The current stu...
ORGANISM(S): Rattus norvegicus (Rat) 
2014-07-22 | PXD000990 | Pride
Rat Brain Nucleus accumbens Lc-ms/ms Label-free quantification 
TranscriptomicsPlane of nutrition prepartum and bovine hepatic gene expression profiles
Cows were selected from two groups of 12 cows enrolled in a large experiment to assess the effects of ad libitum or restricted intake of moderate-energy diets during the entire dry period on pre-partum metabolism and post-partum metabolism and performance. A corn silage-based diet (26% of diet dry ...
ORGANISM(S): Bos taurus 
2010-07-01 | E-GEOD-3331 | biostudies-arrayexpress
TranscriptomicsTemporal bovine liver gene expression
Liver from five Holstein cows fed to current National Research Council (2001) recommendations during the dry period and early lactation was biopsied at -65, -30, -14, 1, 14, 28, and 49 days relative to parturition. cDNA from liver and a reference standard (made from cattle tissues not including liv...
ORGANISM(S): Bos taurus 
2010-06-09 | E-GEOD-2692 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of whole blood incubated with live meningococci
Blood from two donors was incubated for timepoints up to 24 hours in the presence and absence of live meningococci. The donors are labelled NP and SW. 'SWB' refers to blood that was incubated with meningococci; 'Unstim' refers to control blood incubated in the absence of meningococci. Duplicate arr...
ORGANISM(S): Homo sapiens 
2005-12-29 | E-GEOD-3934 | biostudies-arrayexpress
TranscriptomicsDynamic transcriptional response of Microcoleus vaginatus to hydration and dehydration in a desert biological soil crust
Biological soil crusts (BSCs) are cyanobacteria-dominated microbial communities that cover extensive portions of the world’s arid and semi-arid deserts. The infrequent periods of hydration are often too short to allow for dormancy strategies based on sporulation; consequently, survival is based on t...
ORGANISM(S): Microcoleus vaginatus 
2012-10-30 | E-GEOD-40188 | biostudies-arrayexpress
TranscriptomicsTranscriptional and proteomic response of Pseudomonas aeruginosa PAO1 to spaceflight conditions involves Hfq regulation and reveals a role for oxygen
Characterization of bacterial behavior in the microgravity environment of spaceflight is of importance towards risk assessment and prevention of infectious disease during long-term missions. Further, this research field unveils new insights into connections between low fluid-shear regions encountere...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2011-06-28 | E-GEOD-22684 | biostudies-arrayexpress
TranscriptomicsCpG Island methylation variation in placentae of Intra-Uterine Growth Restricted (IUGR) fetuses versus controls
Methylation profiling of CpG Island Methylation of genomic DNA samples extracted from placentae of Intra-Uterine Growth Restricted newborns and gestational age matched controls. These data can be used for methylation comparisons between these two types of samples. The results of such comparisons can...
ORGANISM(S): Homo sapiens 
2011-04-11 | E-GEOD-22326 | biostudies-arrayexpress
TranscriptomicsIdentification of Aneuploidy-tolerating Mutations
Aneuploidy causes a proliferative disadvantage in all cells analyzed to date, yet this condition is associated with a disease characterized by unabated proliferative potential, cancer. The mechanisms that allow cancer cells to tolerate the adverse effects of aneuploidy are not known. To probe this q...
ORGANISM(S): Saccharomyces cerevisiae 
2010-02-24 | E-GEOD-20464 | biostudies-arrayexpress
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