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GenomicsSetDB1 Contributes to Repression of Genes Encoding Developmental Regulators and Maintenance of ES Cell State
Transcription factors that play key roles in regulating embryonic stem (ES) cell state have been identified, but the chromatin regulators that help maintain ES cells are less well understood. A high-throughput shRNA screen was used to identify novel chromatin regulators that influence ES cell state...
ORGANISM(S): Mus musculus 
2009-11-01 | E-GEOD-18371 | biostudies-arrayexpress
UnknownMetabarcoding reveals a high diversity of woody host-associated Phytophthora spp. in soils at public gardens and amenity woodlands in Britain.
Not available
S-EPMC6526010 | biostudies-literature
TranscriptomicsTranscription profiling of intraepithelial and peripheral CTL from patients with celiac disease or cytomegalovirus seropositive patients suggest that a stepwise transformation of CTLs into NK-like cells may underlie immunopathology in various chronic infectious and inflammatory diseases.
Celiac disease is an intestinal inflammatory disorder induced by dietary gluten in genetically susceptible individuals. The mechanisms underlying the massive expansion of interferon g–producing intraepithelial cytotoxic T lymphocytes (CTLs) and the destruction of the epithelial cells lining the sm...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4592 | biostudies-arrayexpress
UnknownSafety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial.
Not available
S-EPMC8213361 | biostudies-literature
GenomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-Seq
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20530 | biostudies-arrayexpress
UnknownGenomewide Association Study of Severe Covid-19 with Respiratory Failure.
Not available
S-EPMC7315890 | biostudies-literature
UnknownAnkyrin-B dysfunction predisposes to arrhythmogenic cardiomyopathy and is amenable to therapy.
Not available
S-EPMC6668697 | biostudies-literature
UnknownCommon genetic variation and susceptibility to partial epilepsies: a genome-wide association study.
Not available
S-EPMC2892941 | biostudies-literature
UnknownEstrogen receptor beta rs1271572 polymorphism and invasive ovarian carcinoma risk: pooled analysis within the Ovarian Cancer Association Consortium.
Not available
S-EPMC3108970 | biostudies-literature
UnknownGenetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study.
Not available
S-EPMC3863710 | biostudies-literature
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