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TranscriptomicsPtrA is required for coordinate regulation of gene expression during phosphate depletion in a marine Synechococcus
The genome of the marine Synechococcus sp. WH8102 displays a minimal regulatory network yet physiological and molecular responses of this organism are tuned to episodic limitation for nitrogen and phosphorus. Microarray analyses have demonstrated a key role for the two-component regulatory system, P...
ORGANISM(S): Synechococcus sp. WH 8102 
2010-04-08 | E-GEOD-18511 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of abx1 deletion or over expression in Streptococcus agalactiae and comparision with the effect of CovS and CovR deletion
Analysis of the impact of the abx1 deletion or over expression on S. agalactaie transcription profile and comparision to the effect of CovS and CovR deletion on transcriptomic profile. Some of the mutants are gene_knock_out mutants, but in other strains we have tested the over expression of the Abx1...
ORGANISM(S): Streptococcus agalactiae 
2013-02-26 | E-MEXP-3703 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of ververt monkey limbus
The limbus is a unique anatomic structure that is highly innervated and vascularized yet sets the boundary for the avascularized cornea. The corneal epithelial stem cells are believed to reside at the limbus. The intrinsic and external molecular signals that modulate the differentiation and prolifer...
ORGANISM(S): Chlorocebus sabaeus 
2008-04-06 | E-GEOD-10683 | biostudies-arrayexpress
GenomicsCistrome of the Aldosterone-activated Mineralocorticoid Receptor in Human Renal Cells
Aldosterone, the main mineralocorticoid hormone in Humans, has a major role in maintaining the hemo-electrolytique homeostasis, by acting in the distal part of nephron. This steroid hormone mainly acts through its binding to a ligand-induced transcription factor, the mineralocorticoid receptor (MR)....
ORGANISM(S): Homo sapiens 
2015-06-12 | E-GEOD-69777 | biostudies-arrayexpress
TranscriptomicsCIT - Homo sapiens - APUP - Genomic aberrations in Lung Adenocarcinoma in Never Smokers
41 lung adenocarcinoma from never-smokers hybridized on Illumina SNP arrays on 13 HumanCNV370-Quadv3 chips. High-resolution array comparative genomic hybridization analysis of lung adenocarcinoma in 41 never smokers for identification of new minimal common regions (MCR) of gain or loss. The SNP arr...
ORGANISM(S): Homo sapiens 
2011-07-28 | E-TABM-1169 | biostudies-arrayexpress
TranscriptomicsA molecular and phenotypic integrative approach to identify a no effect dose level for anti-androgen induced testicular toxicity
With the advent of high information content technologies, especially microarrays, it is pertinent to determine the impact of molecular data on the NOAELs. Consequently, we conducted an integrative study to identify a no transcriptomic effect dose using microarray analyses coupled with qPCR and deter...
ORGANISM(S): Rattus norvegicus 
2011-03-29 | E-GEOD-28202 | biostudies-arrayexpress
TranscriptomicsImpact of sucrose on the tolerance of phenanthrene-phytoremediation
au10-04_phytoremediation; impact of sucrose on the tolerance of phenanthrene Effect of phenanthrene and sucrose - We test 3 conditions plants non-treated (C or t0), plants treated with phenanthrene (P) and plants tread with phenanthrene and sucrose (S). The plants were grown on MS/2 media for 17 day...
ORGANISM(S): Arabidopsis thaliana 
2013-06-28 | E-GEOD-48181 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of non-genotoxic hepatocarcinogens and hepatotoxicants in rat liver
Liver tumors in rodents are frequently induced by non-genotoxic carcinogens. These hepatocarcinogens generally activate hepatic nuclear receptors (e.g., CAR and PXR), resulting in a cascade of signals causing modifications in the expression of genes responsible for several processes involved in carc...
ORGANISM(S): Rattus norvegicus 
2013-07-31 | E-GEOD-39350 | biostudies-arrayexpress
TranscriptomicsNew insights into the molecular mechanisms of 1,3-dinitrobenzene-induced testicular toxicity
Several studies have shown that 1,3-dinitrobenzene (DNB) causes injury to Sertoli cells and induces apoptosis in the surrounding germinal cells in male laboratory rats ; however, the mechanisms by which DNB functions are not well understood. In this context, we have conducted studies using standard ...
ORGANISM(S): Rattus norvegicus 
2012-07-13 | E-GEOD-39344 | biostudies-arrayexpress
MetabolomicsPREDICT: untargeted metabolomic profiling in a Brassica napus (canola) breeding population by GC-MS

Genome-wide association studies (GWAS) identified thousands of genetic loci associated with complex plant traits, including many traits of agronomical importance. However, functional interpretation of GWAS results remains challenging because of large candidate regions due to linkage disequilibriu...

2023-11-20 | MTBLS8056 | MetaboLights
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