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TranscriptomicsA comparison of physiological and transcriptome responses to water deprivation and salt loading in the rat supraoptic nucleus
Salt loading (SL) and water deprivation (WD) are experimental challenges that are often used to study the osmotic circuitry of the brain. Central to this circuit is the supraoptic nucleus (SON) of the hypothalamus, which is responsible for the biosynthesis of the hormones, vasopressin (AVP) and oxyt...
ORGANISM(S): Rattus norvegicus 
2015-02-05 | E-GEOD-65663 | biostudies-arrayexpress
UnknownCharacterization of a Clinically and Biologically Defined Subgroup of Patients with Autism Spectrum Disorder and Identification of a Tailored Combination Treatment.
Not available
S-EPMC11117897 | biostudies-literature
TranscriptomicsMFAP4 is an integrin M-NM-1VM-NM-23/5 ligand involved in vascular remodeling
Arterial injury or occlusive arterial disease may stimulate healing responses, which when overexuberant, leads to restenosis of the injured vessel. This response is influenced by specific integrin signalling in vascular smooth muscle cells (VSMCs). Microfibril-associated protein 4 (MFAP4) colocates ...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-40480 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of neonatal and adult mouse natural killer cells
Comparing global gene expression of neonatal and adult natural killer cells to determine if differences in gene expression suggest that different developmental pathways during hematopoiesis are followed in the fetal and adult mouse to produce mature natural killer cells.
ORGANISM(S): Mus musculus 
2005-10-01 | E-MEXP-354 | biostudies-arrayexpress
TranscriptomicsMiR-34a is dispensable for normal development but its loss accelerates medulloblastoma formation
Previous studies have evaluated the role of miRNAs in the initiation and progression of cancer. MiR-34a was found to be downregulated in several tumors, including medulloblastoma. We here analysed the function of miR-34a in vivo by targeted transgenesis to generate mice with constitutive deletion of...
ORGANISM(S): Mus musculus 
2014-09-22 | E-GEOD-40511 | biostudies-arrayexpress
Transcriptomicsgene expression profile in breast cancer cells with opposing responses to TGF-beta
We aim to test whether our panel of breast cancer cell lines belong to the claudinlow subtype of breast cancer using the classifier published by Prat et al. Breast Cancer Research 12, 2010. For the analysis, we used gene expression data of our cell lines obtained with Illumina bead arrays grown in 2...
ORGANISM(S): Homo sapiens 
2012-09-21 | E-MTAB-1190 | biostudies-arrayexpress
UnknownComparison of Home Antigen Testing With RT-PCR and Viral Culture During the Course of SARS-CoV-2 Infection.
Not available
S-EPMC9055515 | biostudies-literature
TranscriptomicsTGF-beta specific gene expression signatures in breast cancer stem cells
Analyze TGF-beta pathway transcriptional regulation in breast cancer stem cells with different responses upon TGF-beta pathway activation. Total RNA from four breast cell lines grown as mammospheres treated with recombinant TGF-beta or a TGF-beta receptor I inhibitor was used in the analysis.
ORGANISM(S): Homo sapiens 
2012-02-09 | E-MTAB-516 | biostudies-arrayexpress
UnknownDiagnostic genomic analysis is prognostic in AYA patients with ALL treated on an MRD-stratified pediatric protocol.
Not available
S-EPMC12182849 | biostudies-literature
TranscriptomicsHomarus americanus larval development and metamorphosis
Transcriptional profiling of larval stage I - IV of Homarus americanus, for assessment of stage specific developmental gene expression. Individuals from each stage were gathered in July of 2009 and 2010. A reference design was used to permit comparison of all stages. Study aims included assessment o...
ORGANISM(S): Homarus americanus 
2013-12-31 | E-GEOD-45683 | biostudies-arrayexpress
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