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ProteomicsSelective degradation of BRD9 by a DCAF16-recruiting targeted glue: mode of action elucidation and in vivo proof of concept
Prospective discovery of molecular glues degraders for a specific therapeutic target protein of interest is an emerging strategy in drug discovery. Modification of pre-existing ligands with fragments that can alter the protein surface can lead to the creation of novel compounds (‘’targeted glues’’)...
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD062354 | Pride
Global proteomics Orbitrap fusion™ lumos™ tribrid™ Tmt Mv411 
ProteomicsSelective degradation of BRD9 by a DCAF16-recruiting targeted glue: mode of action elucidation and in vivo proof of concept
Prospective discovery of molecular glues degraders for a specific therapeutic target protein of interest is an emerging strategy in drug discovery. Modification of pre-existing ligands with fragments that can alter the protein surface can lead to the creation of novel compounds (‘’targeted glues’’)...
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD062355 | Pride
Tmt Hek293 ip-ms 
TranscriptomicsTranscriptome analysis of renal cancer from the Cancer Genomics of the Kidney (CAGEKID) project
The incidence of renal cell carcinoma (RCC) is increasing worldwide, and its prevalence is particularly high in some parts of Central Europe. The study describes transcriptome sequencing of clear cell RCC (ccRCC), the most common form of the disease, in patients from four different European countri...
ORGANISM(S): Homo sapiens 
2014-10-29 | E-MTAB-3033 | biostudies-arrayexpress
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