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Transcriptional gene silencing controls transposons and other repetitive elements through RNA-directed DNA methylation (RdDM) and heterochromatin formation. A key component of the Arabidopsis RdDM pathway is ARGONAUTE4 (AGO4), which associates with sizs to mediate DNA methylation. Here, we show that...
ORGANISM(S): Arabidopsis thaliana 
Background Zymomonas mobilis ZM4 is a capable ethanologenic bacterium with high ethanol productivity and ethanol tolerance. Previous studies indicated that several stress-related proteins and changes in the ZM4 membrane lipid composition may contribute to ethanol tolerance. However, the molecular m...
ORGANISM(S): Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 
To elucidate underlying mechanisms responsible for enhanced isobutanol tolerance of the gln3 deletion strain, we performed RNA-seq experiments in biological duplicate to compare the transcriptomic profiles of wild type and gln3 deletion strains grown in SC medium with or without 1.3% (v/v) isobutano...
ORGANISM(S): Saccharomyces cerevisiae 
BY4730 cultures were exposed to medium containing dilutions of test agent (Cisplatin (Cis), 600mg/mL; Methylmethane sulfonate (MMS), 0.12% v/v; Bleomycin (Bleo), 0.15U/mL; NaCl, 10mg/mL; ethanol, 15% v/v) for 120 min. Control cultures were either mock-treated with the solvent, DMSO (for comparison t...
ORGANISM(S): Saccharomyces cerevisiae 
RNA polymerase V targets transcriptional silencing components to promoters of protein-coding genes
Approximately 10% of fractures that occur in the United States annually will not heal without intervention. This figure is rising due to an aging population and a rise in conditions that impair bone healing. Current treatments can be marginally effective, costly, and some have adverse effects. A saf...
ORGANISM(S): Homo sapiens (Human) 
2020-07-02 | PXD016017 | Pride
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