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TranscriptomicsHuman pancreatic adenocarcinoma contains a side population resistant to gemcitabine
BACKGROUND: Therapy resistance remains one of the major challenges to improve the prognosis of patients with pancreatic cancer. Chemoresistant cells, which potentially also display cancer stem cell (CSC) characteristics, can be isolated using the side population (SP) technique. Our aim was to search...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-36563 | biostudies-arrayexpress
TranscriptomicsThe side population of human pancreatic cancer expresses cancer stem cell-associated genes
Purpose: To explore the side population (SP) in pancreatic ductal adenocarcinoma (PDAC) for its gene expression profile and its association to cancer stem cells (CSC) and to evaluate the value of genes from its gene signature on patient survival. Experimental design: Side and main population (MP) c...
ORGANISM(S): Homo sapiens 
2014-09-26 | E-GEOD-42404 | biostudies-arrayexpress
TranscriptomicsSide population cells in human primary melanoma
Melanoma remains the most lethal skin cancer, mainly because of high resistance to therapy. Side population (SP) cells are found in many types of cancer and are usually enriched in therapy-resistant as well as tumorigenic cells. Here, we identified a Hoechst dye-effluxing SP in a large series of hum...
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-48838 | biostudies-arrayexpress
TranscriptomicsPituitary tumors contain a (CD31¯/CD45¯ purified) side population with 'tumor stem cell'-associated characteristics [set 2]
Pituitary adenomas cause significant endocrine and mass-related morbidity. Not much is known about mechanisms underlying pituitary tumor pathogenesis. We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor st...
ORGANISM(S): Homo sapiens 
2015-08-04 | E-GEOD-62870 | biostudies-arrayexpress
TranscriptomicsPituitary tumors contain a side population with 'tumor stem cell'-associated characteristics [set 1]
Pituitary adenomas cause significant endocrine and mass-related morbidity. Not much is known about mechanisms underlying pituitary tumor pathogenesis.We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor ste...
ORGANISM(S): Homo sapiens 
2015-08-04 | E-GEOD-62866 | biostudies-arrayexpress
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