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ProteomicsDistinct lactation-associated macrophages exist in murine mammary tissue and human milk
Macrophages are involved in immune defense, organogenesis and tissue homeostasis. They also contribute to the different phases of mammary gland remodeling during development, pregnancy and involution post-lactation. Yet, less is known about the dynamics of mammary gland macrophages in the lactation ...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-23 | PXD041711 | Pride
Mammary gland Macrophages Lactation Milk 
TranscriptomicsRNA sequencing of microglia sorted form tamoxifen treated Sall1CreER/fl and control Sall1fl/fl mice
Microglia are the resident macrophages of the central nervous system (CNS). Gene profiling identified the transcriptional regulator Sall1 as a microglia signature gene. Given the high expression of Sall1 in microglia, we sought to identify its function in vivo. The Sall1CreER allele has been targete...
ORGANISM(S): Mus musculus 
2016-10-19 | E-MTAB-5077 | biostudies-arrayexpress
TranscriptomicsC-Myb+ erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages
Although classified as hematopoietic cells, tissue-resident macrophages are selfrenewing and maintained independently of adult hematopoiesis. While most macrophages originate from embryonic precursors that seed tissues prior to birth, their exact origin is unknown. Using an in utero macrophage deple...
ORGANISM(S): Mus musculus 
2015-04-23 | E-GEOD-66970 | biostudies-arrayexpress
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