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TranscriptomicsKidney development time course
Array Design; Mouse Compugen 22K Spotted Oligo Author; Sean Grimmond Common Reference (Yes/No, ID); Yes Mouse universal Reference (Stratagene) Concentration; 100 Data processing/normalization; Lowess Normalisation GeneSpring) Developmental Stage; embryonic Diseased/Normal; normal Dye Swap; red/green...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-2282 | biostudies-arrayexpress
TranscriptomicsDeep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human Embryonic Stem cells (part 2)
Recent RNA-sequencing studies have shown remarkable complexity in the mammalian transcriptome. The ultimate impact of this complexity on the predicted proteomic output is less well defined. We have undertaken a strand-specific RNA sequencing of multiple cellular RNA fractions (>18Gb) to uncover the ...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-25842 | biostudies-arrayexpress
TranscriptomicsDeep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human Embryonic Stem cells
Cytoplasmic polyadenylated RNA from human embryonic stem cells (HES2) was separated on a 1.2% agarose and gel slices were excised corresponding to the following sizes: 0 to 0.5 kb; 0.5-2 kb; 2-3.5 kb; 3.5-6.5 kb and 6.5-20+ kb. Slices were dissolved and extracted RNA (1% of each fraction) was run on...
ORGANISM(S): Homo sapiens 
2010-10-20 | E-GEOD-24355 | biostudies-arrayexpress
TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of mouse BMM and TEPM to lipopolysaccharide (LPS)
Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing inter-species differences in the transcriptional responses of primary human and mouse macrophages to the TLR4 agon...
ORGANISM(S): Mus musculus 
2012-03-28 | E-GEOD-19490 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS)
Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing inter-species differences in the transcriptional responses of primary human and mouse macrophages to the TLR4 agon...
ORGANISM(S): Homo sapiens 
2012-03-28 | E-GEOD-19482 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression and intron retention during development in a U12-type splicing-deficient zebrafish mutant [RNA-seq]
To determine the global impact of the clbn mutation on gene expression and efficiency of U2- and U12-type splicing, we analyzed the transcriptome of 108hpf wt and clbn mutant larvae by microarrays and RNA sequencing. RNAseq data was used to characterize intron retention of U2-type and U12-type intro...
ORGANISM(S): Danio rerio 
2014-02-05 | E-GEOD-53758 | biostudies-arrayexpress
UnknownSnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sample.
Not available
S-EPMC3935918 | biostudies-literature
UnknownMicroRNA-182-5p targets a network of genes involved in DNA repair
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-38593 | biostudies-other
UnknownMicroRNA-182-5p targets a network of genes involved in DNA repair.
Not available
S-EPMC3543090 | biostudies-literature
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