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TranscriptomicsEvaluation of the amplicons for SNP typing (allele bias) and locus bias using Illumina 550-Duo BeadChip
Highly specific amplification of complex DNA pools without bias or template-independent products (TIPs) remains a challenge. We have developed a procedure using phi29 DNA polymerase and trehalose and optimized control of amplification to create micrograms of specific amplicons without TIPs from down...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-12732 | biostudies-arrayexpress
TranscriptomicsHigh-resolution comparative genome hybridization survey of healthy individuals (chromosome 22)
HighRes-CGH arrays that utilize ≈385,000 distinct oligonucleotide probes to cover chromosome 22 at 85 bp resolution (tiling path step size) were designed and synthesized as previously described (Urban et al., Proc Natl Acad Sci U S A. 2006;103(12):4534-9; see also GSE4240 record). Here, two health...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-6010 | biostudies-arrayexpress
TranscriptomicsTranscriptome Sequencing from Diverse Human Populations Reveals Differentiated Regulatory Architecture
To understand the full range of expression variation, alternative splicing, and the genetics of regulatory variation in humans, we have sequenced the genomes, exomes, and transcriptomes of 45 individuals in the Human Genome Diversity Panel (HGDP) from seven worldwide populations that span the geogra...
ORGANISM(S): Homo sapiens 
2014-08-25 | E-GEOD-54308 | biostudies-arrayexpress
GenomicsHuman variation in PolII and NF-KappaB binding (ChIP-seq study with NF-KappaB)
We examined genome-wide variation in transcription factor binding in different individuals and a chimpanzee using chromatin immunoprecipitation followed by massively-parallel sequencing (ChIP-Seq). The binding sites of RNA Polymerase II (Pol II) as well as a key regulator of immune responses, NFkB, ...
ORGANISM(S): Homo sapiens 
2010-03-22 | E-GEOD-19485 | biostudies-arrayexpress
GenomicsHuman variation in PolII and NF-KappaB binding (ChIP-seq study with Pol II)
We examined genome-wide variation in transcription factor binding in different individuals and a chimpanzee using chromatin immunoprecipitation followed by massively-parallel sequencing (ChIP-Seq). The binding sites of RNA Polymerase II (Pol II) as well as a key regulator of immune responses, NFkB, ...
ORGANISM(S): Pan troglodytes 
2010-03-22 | E-GEOD-19484 | biostudies-arrayexpress
TranscriptomicsHuman variation in PolII and NF-KappaB binding (RNA-seq study with TNF-alpha induced)
We examined genome-wide variation in transcription factor binding in different individuals and a chimpanzee using chromatin immunoprecipitation followed by massively-parallel sequencing (ChIP-Seq). The binding sites of RNA Polymerase II (Pol II) as well as a key regulator of immune responses, NFkB, ...
ORGANISM(S): Homo sapiens 
2010-03-22 | E-GEOD-19481 | biostudies-arrayexpress
TranscriptomicsHuman variation in PolII and NF-KappaB binding (RNA-seq study uninduced by TNF-alpha)
We examined genome-wide variation in transcription factor binding in different individuals and a chimpanzee using chromatin immunoprecipitation followed by massively-parallel sequencing (ChIP-Seq). The binding sites of RNA Polymerase II (Pol II) as well as a key regulator of immune responses, NFkB, ...
ORGANISM(S): Homo sapiens 
2010-03-22 | E-GEOD-19466 | biostudies-arrayexpress
Transcriptomics8-chip high-resolution aCGH experiment NA15510 vs. NA18505
We introduce high-throughput and massive paired-end mapping (PEM), a large-scale genome sequencing method to identify SVs 3 kb or larger that combines the rescue and capture of paired-ends of 3 kb fragments, massive 454 Sequencing, and a computational approach to map DNA reads onto a reference genom...
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-9002 | biostudies-arrayexpress
Proteomics,MultiomicsHS_iPOP_PBMC2011_SecondBatch_81213151614_r01
HS_iPOP_PBMC2011_SecondBatch_81213151614_r01
ORGANISM(S): Homo Sapiens (human) 
2012-12-31 | PAe003751 | PeptideAtlas
Proteomics,MultiomicsHS_iPOP_PBMC2011_SecondBatch_81213151614_r02
HS_iPOP_PBMC2011_SecondBatch_81213151614_r02
ORGANISM(S): Homo Sapiens (human) 
2012-12-31 | PAe003771 | PeptideAtlas
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